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A case of squamous cell carcinoma of the nasal cavity in a patient with granulomatosis with polyangiitis (Wegener granulomatosis)

January 14, 2018  |  Edward C. Kuan, MD, MBA; Kevin A. Peng, MD; Lyndon O. Gonzalez, MD; Joel A. Sercarz, MD


We report a rare case of squamous cell carcinoma (SCC) of the nasal cavity arising in a patient with granulomatosis with polyangiitis (GPA). The patient was a 35-year-old man who had been diagnosed 15 years earlier with GPA and treated medically for sinonasal, pulmonary, and...

Endoscopic finding of two osteomas in the frontal sinus

January 14, 2018  |  Jong Seung Kim, MD; Sam Hyun Kwon, MD, PhD

Most osteomas are asymptomatic, so these tumors are often detected incidentally on paranasal CT scans.

Inferior turbinate reduction: Diode laser or conventional partial turbinectomy?

January 14, 2018  |  Venkatesh Doreyawar, MS; Raveendra P. Gadag, MS; Dandi Narasaiah Manjunath, MS; Shivalingappa B. Javali, MPhil, PhD; Nagaraj Maradi, MBBS; Deekshit Shetty, MBBS


Hypertrophy of the inferior nasal turbinate is one of the most common causes of nasal obstruction. The diode laser has proven to be as effective as other lasers for this indication. Our objective was to study various outcomes associated with the use of the diode laser, such as...

The effects of mometasone furoate and strontium chloride in a rat model of allergic rhinitis

January 14, 2018  |  Emine Elif Altuntas, MD; Omer Tamer Dogan, MD; Bulent Sarac, MD; Nergiz Hacer Turgut, PhD; Kasim Durmus, MD; Melih Akyol, MD


Neurogenic inflammation plays a role in the pathophysiology of allergic rhinitis. Highly effective in reducing the sensory irritation caused by some substances, strontium salts directly affect C-type nerve fibers. The aim of this study was to compare the efficacy of mometasone...

A South African first: Congenital absence of the cartilaginous nasal septum

January 14, 2018  |  Yahya Atiya, MBBCh, MMed (ORL), FCORL


Congenital absence of the cartilaginous nasal septum has been reported just once in the literature. We present a case of a young child, diagnosed by exclusion, with complete agenesis of the cartilaginous septum. We believe it is only the second case worldwide, and the first in...

The sensitivity and specificity of touch preparation for rapid diagnosis of invasive fungal sinusitis: A pilot study

January 14, 2018  |  Theodore A. Schuman, MD; Josephine H. Nguyen, MD; Joshua C. Yelverton, MD; Jorge A. Almenara, PhD; Celeste N. Powers, MD, PhD


Invasive fungal sinusitis is a morbid pathology that typically affects immunocompromised patients and may quickly progress to fulminant disease. The purpose of this study was to measure the sensitivity and specificity of touch preparation of nasal debridement specimens as a...

Use of the microdebrider in the surgical management of rhinophyma

January 14, 2018  |  Winsion Chow, MD, MSc; Goran Jeremic, MD, FRCSC; Leigh Sowerby, MD, FRCSC


Rhinophyma is a disfiguring end-stage manifestation of acne rosacea. It is characterized by a painless hyperplasia of the sebaceous glands and connective tissues of the nose. Numerous surgical modalities-including scalpel surgery, dermabrasion, CO2 laser ablation, and...

Endoscopic view of a mucocele obstructing a middle meatal antrostomy

January 14, 2018  |  Eiji Yanagisawa, MD, FACS; Dewey A. Christmas, MD; Joseph P. Mirante, MD, MBA, FACS

Mucoceles can occur naturally as mucus retention cysts or after sinus surgery, by ostial obstruction and formation of a lesion lined by low columnar epithelium.

Contact allergy to benzalkonium chloride in patients using a steroid nasal spray: A report of 3 cases

January 14, 2018  |  Jerome Rene Lechien, MD, PhD, MS; Pedro Costa de Araujo, MD; Lisa G. De Marrez, BSc; Jean-Luc Halloy, MD; Mohamad Khalife, MD; Sven Saussez, MD, PhD


Benzalkonium chloride (BAC) is a bactericidal preservative excipient commonly found in steroid nasal sprays used to treat allergic rhinitis and nasal polyposis. In rare cases, BAC can be responsible for type I and type IV hypersensitivity reactions that can manifest as...

Endoscopic endonasal management of recurrent maxillary mucoceles using biliary T-tube stenting

December 12, 2017  |  Noritsugu Ono, MD; Shin Ito, MD; Hirotomo Homma, MD; Hiroko Okada, MD; Junko Murata, MD; Katsuhisa Ikeda, MD, PhD


Mucoceles of the paranasal sinus can be managed endoscopically with an extremely low recurrence rate. Frontal sinus mucoceles can sometimes be prevented from closing and reforming by stenting, which to the best of our knowledge has not yet been reported in the maxillary sinus....

Intracranial abscess formation following sphenoid sinus occlusion with nasoseptal flap skull base reconstruction: A cautionary tale

December 12, 2017  |  George S. Tarasidis, MD; Jeremiah A. Alt, MD, PhD; Richard R. Orlandi, MD


The formation of an intracranial abscess secondary to sphenoid sinus occlusion after nasoseptal flap skull base reconstruction has not been previously described. We report such a case that occurred at our institution in a 23-year-old man who underwent flap reconstruction for a...

5-HT7 receptors are over-expressed in patients with nasal polyps

December 12, 2017  |  Muhammed Yayla, PhD; Zekai Halici, MD; Duygu Kose, MD; Arzu Tatar, MD; Mustafa Sitki Gozeler, MB


Nasal polyposis (NP) is an inflammatory disease of the paranasal sinuses and nasal cavity. The primary purpose of our study is to determine the expression of 5-HT7 receptors both in nasal polyps and in healthy tissue in the nasal cavity. The subsequent aim is to compare the...