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Oropharynx

Treatment outcomes in HPV-negative oropharyngeal cancer: Surgery plus radiotherapy vs. definitive chemoradiotherapy

August 22, 2018  |  Dominique Rash, MD; Megan E. Daly, MD; Blythe Durbin-Johnson, PhD; Andrew T. Vaughan, PhD; Allen M. Chen, MD

Abstract

We performed a retrospective study to compare clinical outcomes among 51 consecutively presenting patients-38 men and 13 women, aged 46 to 74 years (median: 57)-with locally advanced human papillomavirus (HPV)-negative oropharyngeal cancer who were treated with either primary...

A rare cause of dysphagia: Pyriform sinus atypical lipomatous tumor

April 30, 2018  |  Yoseph A. Kram, MD; James M. McCann, DMD, MS; Joseph Golden, MD; Eric Wirtz, MD

Surgical excision in the hypopharynx can be challenging because of inadequate access and visualization.

Relationship between dysarthria and oral-oropharyngeal dysphagia: The current evidence

March 14, 2018  |  Brandon J. Wang, BA, BBA; Felicia L. Carter, MA, CCC-SLP; Kenneth W. Altman, MD, PhD

Abstract

There is a high prevalence of dysphagia among patients with neuromuscular diseases and cerebrovascular diseases, and its consequences can be profound. However, the correlation between dysarthria and oral-oropharyngeal dysphagia remains unclear. We conducted a literature review...

Long-term recurrence-free survival after an unplanned reduction in radiotherapy for HPV-positive oropharyngeal SCC: Two cases and a review of the literature

July 18, 2017  |  Jason Liu, BS; David Goldenberg, MD; Salah Almokadem, MD; Henry Crist, MD; Heath B. Mackley, MD, FACRO

Abstract

There is currently no clear distinction between the treatment of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC has been demonstrated to be more radiosensitive than its HPV-negative counterpart. Despite this, patients with HPV-...

Obstructing in utero oropharyngeal mass: Case report of a lymphatic malformation arising within an oropharyngeal teratoma

January 25, 2017  |  Todd J. Wannemuehler, MD; Christopher R. Deig, BA; Brandon P. Brown, MD; Stuart A. Morgenstein, DO

Abstract

An ex utero intrapartum treatment procedure was performed to deliver a fetus with a multiseptated, entirely cystic, 4.5 x 5.0 x 4.0-cm mass occupying the oropharynx and oral cavity with protrusion from the mouth. Surgical excision was performed, and final pathologic diagnosis...

Lingual osseous choristoma

July 18, 2016  |  Daniel T. Ginat, MD, MS; Louis Portugal, MD

When they occur, symptoms of lingual osseous choristomas may include globus sensation, dysphagia, gagging, nausea, and irritation.

Granulomatous ulcers of the nose and oropharynx: Lupus vulgaris revisited

February 24, 2016  |  Mainak Dutta, MS; Soumya Ghatak, MS; Ramanuj Sinha, MS, DNB

Lupus vulgaris manifests as a postprimary chronic granulomatous ulcer in patients with moderate to good immunity.

Upper aerodigestive amyloidosis

July 21, 2015  |  Jaime Eaglin Moore, MD; Amanda Hu, MD; Al Hillel, MD

As the patient was asymptomatic, close observation and only laser excision were recommended if the patient's condition progressed.

Metastatic squamous cell carcinoma of the tonsil presenting as otorrhea: A case report

January 19, 2015  |  Eelam Adil, MD; Dhave Setabutr, MD; Soha N. Ghossaini, MD; David Goldenberg, MD, FACS

Abstract

We describe the case of a 52-year-old man with a history of squamous cell carcinoma (SCC) of the tonsil who presented with right subacute otalgia and otorrhea. Dedicated computed tomography of the temporal bones showed opacification within the mastoid process with destruction...

Solitary myofibroma of the oropharynx causing airway obstruction in an adult

September 18, 2014  |  Harrison W. Lin, MD; David Jung, MD, PhD; Linda N. Lee, MD; Peter M. Sadow, MD, PhD; James W. Rocco, MD, PhD

Abstract

Myofibromas are benign neoplasms believed to be the most common fibrous proliferation of childhood. We present an unusual case of a 44-year-old woman who developed acute airway obstruction from a myofibroma in the oropharynx and accordingly required emergent tracheotomy tube...

Transoral robotic surgery and oropharyngeal cancer: A literature review

August 28, 2014  |  Paraig O'Leary, MD; Thomas Kjaergaard, MD, PhD

Abstract

The incidence of head and neck squamous cell carcinoma has risen steadily over the past decade due to the increase in cancers associated with the human papillomavirus (HPV). The prognosis for the treatment of this type of cancer with radiotherapy and chemoradiotherapy is good....

Madelung disease: Multiple symmetric lipomatosis

March 19, 2014  |  Enrique Palacios, MD, FACR; Harold R. Neitzschman, MD, FACR; Jeremy Nguyen, MD

Patients with multiple symmetric lipomatosis commonly also suffer from various neuropathies, especially paresthesias and autonomic neuropathy.

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