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Larynx

Coexistent chronic myelogenous leukemia with squamous cell carcinoma of the larynx associated with NOD2/CARD15 mutation in a young adult

June 14, 2016  |  Marcin Fraczek, MD; Agnieszka Stembalska, MD; Pawel Karpinski, MD; Tomasz Krecicki, MD

Abstract

We report the case of a 37-year-old man with human papillomavirus-positive squamous cell carcinoma of the larynx coexisting with chronic myelogenous leukemia. The patient had no history of smoking or alcohol consumption. Within a few months, his rapidly growing tumor was...

p53 codon 72 polymorphism and its overexpression in patients with laryngeal carcinoma: Prognostic implications

June 14, 2016  |  Gopika Kalsotra, MD; Ashok K. Gupta, MD; Rijuneeta Gupta, MD; Ritu Rathi, PhD; Rajender Prasad, PhD

Abstract

Abnormalities in the p53 gene are the most common genetic alterations seen in laryngeal carcinoma. No data exist regarding the association between laryngeal carcinoma and a distinct codon 72 variant and its expression. We conducted a prospective study (1) to analyze the p53...

Dietary consumption patterns and laryngeal cancer risk

June 14, 2016  |  Petros V. Vlastarakos, MD, MSc, PhD; Andrianna Vassileiou, MD, PhD; Evie Delicha, MSc; Dimitrios Kikidis, MD, MSc; Dimosthenis Protopapas, MD, PhD; Thomas P. Nikolopoulos, MD, DM, PhD

Abstract

We conducted a case-control study to investigate the effect of diet on laryngeal carcinogenesis. Our study population was made up of 140 participants-70 patients with laryngeal cancer (LC) and 70 controls with a non-neoplastic condition that was unrelated to diet, smoking, or...

Primary NK/T-cell lymphoma of the larynx: Report of 2 cases and review of the English-, Japanese-, and Chinese-language literature

April 30, 2016  |  Su-Yu Zhu, MD; Yuan Yuan, MD; Ke Liu, MD, MSc; Liang Zeng, MD, PhD; Ju-Mei Zhou, MD, PhD; Qiong-Hui Lu, MD; Zai-Jie Huang, MD

Abstract

Natural killer/T (NK/T) -cell lymphoma in the larynx is extremely rare, as only 29 cases have been previously reported in the English-language, Japanese-language, and Chinese-language literature. Its characteristics have never been systematically illustrated. We report 2 new...

Thymoma with an incidental benign laryngeal mass mimicking laryngeal carcinoma: Case report

February 24, 2016  |  Gokce Simsek, MD; Istemihan Akin, MD; Cem Saka, MD; Fulya Koybasioglu, MD

Abstract

Thymic carcinomas are rarely seen. Because of recurrent laryngeal nerve involvement, hoarseness is a common presenting symptom. Persistent hoarseness in a male smoker past his fifth decade is also a distinctive symptom for laryngeal carcinoma. Stroboscopic laryngeal examination...

Novel injection technique into the interarytenoid area to treat dysphagia

February 24, 2016  |  Meghan Brooking, DO; Amanda Hu, MD, FRCSC; Robert T. Sataloff, MD, DMA, FACS

Augmentation of the interarytenoid space is a simple and innovative alternative to the traditional paraglottic space injection.

Laryngotracheal mucormycosis: Report of a case

January 22, 2016  |  Jillian Mattioni, DO; Joel E. Portnoy, MD; Jaime Eaglin Moore, MD; David Carlson, DO; Robert T. Sataloff, MD, DMA, FACS

Abstract

Airway mucormycosis is a deadly opportunistic infection that affects immunocompromised persons, particularly diabetics and those undergoing chemotherapy. Although it is typically a pulmonary or sinonasal infection, mucormycosis can affect the larynx and trachea, with...

Laryngeal tuberculosis: A public health concern

October 31, 2015  |  Matthew B. Zavod, MD, FACS

Physical examination findings in patients with laryngeal tuberculosis vary, but they can include edema, hyperemia, nodularity, ulcerations, exophytic mass, and obliteration of anatomic landmarks.

Laryngofissure for resection of a recurrent saccular cyst

October 31, 2015  |  Reed C. Gilbow, BS; J. Mark Reed, MD; Jeffrey D. Carron, MD

Congenital saccular cysts represent a rare cause of airway obstruction and inspiratory stridor in infants.

Laryngeal neuromas in a case of multiple endocrine neoplasia type 2B

October 31, 2015  |  Stanley W. McClurg, MD; Paul E. Wakely Jr., MD; Eugene G. Chio, MD

Abstract

Mucosal neuromas of the larynx in the setting of multiple endocrine neoplasia type 2B (MEN-2B) are extremely rare; to the best of our knowledge, only 2 other cases have been previously reported in the world literature. We describe a new case, which occurred in a 30-year old...

Globus sensation and laryngopharyngeal reflux

October 31, 2015  |  Michael J. Knabel, BS; Jonathan M. Bock, MD, FACS

Some study results have suggested that psychological factors such as depression and anxiety can influence the etiology of globus.

Laryngeal neurofibroma

October 31, 2015  |  Andreas Anagiotos, MD; Dirk Beutner, MD

Neurofibromas are rarely seen in the larynx. Common symptoms are stridor, hoarseness, dysphagia, dysphonia, and globus sensation.

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