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Persistent local demucosalization after endoscopic sinus surgery: A report of 3 cases

November 8, 2018  |  Conner J. Massey, MD; Menka M. Sanghvi, MD; Thomas R. Troost, MD, PhD; Vijay K. Anand, MD; Ameet Singh, MD


Mucosal preservation is paramount to achieving successful outcomes after endoscopic sinus surgery (ESS). Despite best surgical practices and implementation of evidenced-based postoperative care, patients in rare cases might exhibit persistent demucosalization that is...

Invasive fungal rhinosinusitis: An Indian perspective

November 8, 2018  |  Swati Agrawal, MS, DNB; Sandeep Arora, MS, DNB; Nishi Sharma, MS, DNB


Invasive fungal rhinosinusitis (IFRS) is a fatal disease of the nose and paranasal sinuses that typically affects immunocompromised patients. Data on this disorder, which is rare and difficult to diagnose, are lacking in the literature. We collected comprehensive data from 9...

Chronic otitis media with effusion in chronic sinusitis with polyps

August 22, 2018  |  Mary Daval, MD; Herve; Picard, MD, MSc; Emilie Bequignon, MD; Philippe Bedbeder, MD; Andre Coste, MD, PhD; Denis Ayache, MD, PhD; Virginie Escabasse, MD, PhD


The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear. We conducted a cross-sectional study of 80 consecutively presenting patients-42 males and 38 females, aged 15 to 76 years (median: 48)-who were...

Antibiotics, steroids, and combination therapy in chronic rhinosinusitis without nasal polyps in adults

June 28, 2018  |  Yuan F. Liu, MD; Clare M. Richardson, MD; Stewart H. Bernard, MD; Christopher A. Church, MD; Kristin A. Seiberling, MD


Despite a lack of robust data regarding their efficacy, oral antibiotics and steroids remain two of the most common treatments for chronic rhinosinusitis without nasal polyps (CRSsNP). We sought to objectively compare the efficacy of antibiotics and steroids, independently and...

Histopathologic evaluation of Ecballium elaterium applied to nasal mucosa in a rat rhinosinusitis model

June 28, 2018  |  Can Mehmet Eti, MD; Yusuf Vayisoglu, MD; Berkan Kardas, MD; Rabia Bozdogan Arpaci, MD; Elif Sahin Horasan, MD; Arzu Kanik, PhD; Neslihan Eti, MD; Serap Yalin, BScPhm; Derya Umit Talas, MD


This study aimed to evaluate the antimicrobial effects of the medicinal plant Ecballium elaterium, which is topically applied as a traditional medicine for the treatment of rhinosinusitis. Pure and extract forms of E elaterium were applied to the nasal cavity of...

Powered irrigation with suction evacuation for chronic rhinosinusitis in the office setting: A pilot study

April 30, 2018  |  Margherita Bruni, MD; Lindsey E. Ryan, MD; Mark H. Tabor, MD


Bacterial infections in the form of adherent biofilms are frequently implicated in the pathogenesis and recalcitrance of chronic rhinosinusitis. The Hydrodebrider, a disposable powered irrigation and suction device, has been developed specifically to remove biofilm from the...

Alternative therapies for chronic rhinosinusitis: A review

March 14, 2018  |  Aaron S. Griffin, MBBS, BSci; Peter Cabot, PhD, BSci; Ben Wallwork, PhD, MBBS, FRACS; Ben Panizza, MBA, MBBS, FRACS


The use of alternative medicine in chronic rhinosinusitis (CRS) continues to increase in popularity, for the most part without meeting the burden of being based on sound clinical evidence. New and emerging treatments, both natural and developed, are numerous, and it remains a...

Study of factors responsible for recidivism in allergic fungal rhinosinusitis

September 18, 2017  |  Bipin Kishore Prasad, MS


Patients with allergic fungal rhinosinusitis (AFRS) are typically atopic and immunocompetent. Despite combined modality treatment based on surgery and immunomodulation, the potential for recidivism is well recognized. A study was conducted in a military hospital in India to...

TNF-Alpha inhibitor as a cause of refractory suppurative laryngitis and rhinosinusitis

September 18, 2017  |  Sevtap Akbulut, MD; Lyndsay L. Madden, DO; Berrylin J. Ferguson, MD, FACS; Clark A. Rosen, MD, FACS

Discontinuation of TNF-α inhibitors is recommended in patients with bacterial infections requiring antibiotic therapy or those with severe upper respiratory infection.

Unusual case of chronic maxillary rhinosinusitis

March 24, 2017  |  Jérôme R. Lechien, MD, MSc; Julien W. Hsieh, MD; Sven Saussez, MD, PhD

Although maxillary rhinosinusitis due to migration of a distractor is rare, it must be suspected in all patients with a history of dysmorphism surgery and unilateral rhinosinusitis.

Chronic invasive fungal sinusitis causing a pathologic Le Fort I fracture in an immunocompetent patient

September 19, 2016  |  Amy L. Richter, MD; K. Kelly Gallagher, MD


We describe the case of a 77-year-old immunocompetent woman with a history of chronic rhinosinusitis who presented with a pathologic Le Fort I fracture after a forceful sneeze. Imaging revealed diffuse sinus opacification and a Le Fort type I complex fracture involving the...

Mulberry hypertrophy and accompanying sinonasal pathologies: A review of 68 cases

August 21, 2016  |  Davut Akduman, MD; Mehmet Haksever, MD; Muhammed Yanilmaz, MD; Fevzi Solmaz, MD


Mulberry hypertrophy occasionally coexists with sinonasal pathologies. There are very few reports in the literature on this clinical entity. We conducted a retrospective study to draw attention to this condition in the context of accompanying sinonasal pathologies. Our study...


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