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Late-onset complications after chemoradiation for head and neck carcinomas

August 22, 2013  |  Marc I. Surkin, MD, FACS; Sandra A. Schwartz, MS, CCC-SLP; and Deborah A. Markiewicz, MD


Acute complications from chemoradiation for head and neck cancers are relatively common. These can be minor or severe and can have a significant impact on the patient's quality of life. The incidence of late-onset (>5 years after cancer cure) complications is unknown, but...

Human papillomavirus and tobacco use in tongue base cancers

August 22, 2013  |  Daniel L. Stoler, PhD; Philip J. Smaldino, MS; Huferesh K. Darbary, PhD; Maureen A. Sullivan, DDS; Saurin R. Popat, MD, MBA; Wesley L. Hicks Jr., MD; Mihai Merzianu, MD; Daniel P. Gaile, PhD; Garth R. Anderson, PhD; and Thom R. Loree, MD, FACS


Human papillomavirus 16 (HPV-16) infection and tobacco use are associated with human oropharyngeal cancers. We conducted a study of the role of HPV and tobacco use in base of the tongue (BOT) cancers. DNA from 34 such cancers was subjected to HPV-16 and HPV-18-specific...

Case report: Metastatic small-cell lung carcinoma of the external auditory canal

November 1, 2012  |  Moshe Hain, MD; Edit Feldberg, MD; and Doron Halperin, MD


We report the case of a 73-year-old man who developed metastatic small-cell lung cancer to the bony external auditory canal (EAC). The patient had only recently been diagnosed with his primary carcinoma. The metastasis presented as a bulky, fleshy, bleeding mass in the right...

Prostate cancer metastatic to the larynx: A case report

September 7, 2012  |  Edward E. Katime, MD; Jasvir S. Khurana, MD; Oneida A. Arosarena, MD


Prostate cancer, which is the most common cancer among men, rarely metastasizes to the neck. We report a case of prostatic carcinoma that metastasized to the larynx in a 71-year-old man who presented with hoarseness and shortness of breath. Computed...

Recurrent pre-B-cell acute lymphoblastic leukemia in the middle ear: A form of granulocytic sarcoma

July 5, 2012  |  David Manning, MD; Enrique Palacios, MD, FACR; Harold Neitzschman, MD, FACR

Leukemia of the middle ear easily can be misidentified as acute otitis media or Bell palsy. It occurs most often in children 2 to 5 years of age and in the elderly population.

Voice and swallowing disorders: Functional results and quality of life following supracricoid laryngectomy with cricohyoidoepiglottopexy

October 1, 2009  |  Juliana Godoy Portas, SLP, Débora dos Santos Queija, SLP, Leonora Pereira Arine, SLP, Alessandra Sampaio Ferreira, SLP, Rogério A. Dedivitis, MD, PhD, Carlos Neutzling Lehn, MD, PhD, and Ana Paula Brandão Barros, SLP, PhD


We conducted a prospective study of 11 patients with laryngeal cancer who underwent supracricoid laryngectomy with cricohyoidoepiglottopexy. Our goal was to evaluate their postoperative voice and swallowing function and to ascertain the impact that surgery had on patient-...

Adjuvant external-beam radiotherapy in patients with high-risk well-differentiated thyroid cancer

July 1, 2009  |  Peter V. Chen, MD, MS, Ryan Osborne, MD, Eugene Ahn, MD, Sofia Avitia, MD, Elliot Abemayor, MD, PhD, and Guy Juillard, MD


The role of adjuvant external-beam radiation therapy (EBRT) in well-differentiated thyroid cancer is not well delineated. Many clinicians rely solely on iodine 131 (131I) to destroy thyroid remnants following thyroidectomy. However, the lesser uptake of isotope in...

Training in the primary prevention and early detection of oral cancer: Pilot study of its impact on clinicians' perceptions and intentions

January 1, 2009  |  Charles W. LeHew, PhD, Joel B. Epstein, DMD, MSD, Anne Koerber, DDS, PhD, and Linda M. Kaste, DDS, PhD


In this pilot study, we tested a new program for training medical care providers in the primary prevention and early detection of oral cancer. The training program consisted of two modules: (1) oral cancer epidemiology and head and neck examinations for the early detection of...

Transthoracic/transcervical approach to cervicothoracic thyroid cancer

September 26, 2008  |  Sofia Avitia, MD and Ryan F. Osborne, MD, FACS

Personality changes and the role of counseling in the rehabilitation of patients with laryngeal cancer

August 1, 2008  |  Deepika Sharma, BSc, Anu N. Nagarkar, PhD, Pankaj Jindal, BSc, Rajinder Kaur, PhD, and Ashok K. Gupta, MS


We conducted a study of 65 adults who had undergone laryngectomy for the treatment of laryngeal cancer. Our goal was to identify any abnormal personality traits in these patients and to assess the effect that psychological counseling might have on correcting these abnormalities...

Metastatic ovarian cancer in the head and neck

June 1, 2008  |  Sofia Avitia, MD, Jason S. Hamilton, MD, and Ryan F. Osborne, MD, FACS

Influence of long-term airflow deprivation on the dimensions of the nasal cavity: A study of laryngectomy patients using acoustic rhinometry

August 1, 2007  |  Ozan Bagis Ozgursoy, MD; Gursel Dursun, MD
We conducted a prospective study to investigate the long-term effect of nasal airflow deprivation on nasal...


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