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A rare case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma

November 8, 2018  |  Tsutomu Nomura, MD, DDS, PhD; Daisuke Maki, MD; Fumihiko Matsumoto, MD, PhD; Taisuke Mori, DDS, PhD; Seichi Yoshimoto, MD, PhD


Lacrimal sac tumors are rare and difficult to diagnose. We present a case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma in a 73-year-old woman who presented with swelling of the inner canthus. Biopsy identified the growth as an adenocarcinoma. After...

Nasopharyngeal papillary adenocarcinoma

December 12, 2017  |  Lester D. Thompson, MD

Nasopharyngeal papillary adenocarcinoma may appear grossly as an exophytic, nodular, or polypoid mass, sometimes gritty if psammoma bodies are present.

OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report

April 30, 2016  |  Kiyoshi Makiyama, PhD, MD; Ryoji Hirai, PhD, MD; Fusako Iikuni, MD; Atsuo Ikeda, MD; Hirotaka Tomomatsu, MD


OK-432 is an immunomodulator that has been reported to be efficacious as an injection therapy for cervical lymphomas and ranulas. We performed OK-432 injection therapy to treat a cystadenocarcinoma of the parotid gland in a 72-year-old man. The 50 x 46-mm tumor was located in...

Unusual primary tumors presenting as papillary carcinomas metastatic to the neck

October 31, 2015  |  Agnes Dupret-Bories, MD, PhD; Marc Wilt, MD; Pierre Kennel, MD; Anne Charpiot, MD, PhD; Jean-Francois Rodier, MD, FACS


The presence of a metastatic papillary carcinoma in the neck is presumptive evidence of a primary thyroid neoplasm since neck metastases of other primary tumors are uncommon. Immunohistochemical studies may be required to diagnose these metastases. We report 2 cases in which an...

Primary thyroid-like papillary adenocarcinoma of the nasal septum: A case report

February 2, 2015  |  Kerem Ozturk, MD; Rasit Midilli, MD; Ali Veral, MD; Yesim Ertan, MD; Bulent Karci, MD


Primary thyroid-like papillary adenocarcinomas are extremely rare neoplasms that generally originate in the nasopharynx. We report the case of a 24-year-old woman who was diagnosed with a thyroid-like papillary adenocarcinoma that originated in the nasal septum. The tumor was...

Ceruminous adenocarcinoma of the ear

May 8, 2014  |  Jagdeep Singh Virk, MA (Cantab), MRCS, DOHNS; Gaurav Kumar, FRCS(ORL-HNS); Sherif Khalil, MS, FRCS(ORL-HNS), MD

Ceruminous carcinomas are extremely rare and tend to present as a mass or with otalgia. They are difficult to diagnose histopathologically (in part due to varied and nonstandardized nomenclature).

Polymorphous low-grade adenocarcinoma

January 21, 2014  |  Lester D.R. Thompson, MD

PLGA affects the palate (60% of cases) most commonly, especially at the mucosal junction of the hard and soft palates; the next most common sites are the cheek and the lip, often the upper lip.

Primary adenocarcinoma of the frontal sinus

October 27, 2011  |  Raman Wadhera, MS, S.P. Gulati, MS, Ajay Garg, MS, Anju Ghai, MD, and Sanjay Kumar, MD


When tumor involvement of the frontal sinus occurs, it is usually the result of the direct spread of the mass from the nasal cavity or anterior ethmoid sinuses. Primary frontal sinus tumors are extremely rare. We describe a case of primary adenocarcinoma of the frontal sinus in...

Clear cell adenocarcinoma of the base of the tongue: A case report and review of the literature

May 1, 2011  |  Augusto Pietro Casani, MD, Manuela Marchetti, MD, Veronica Seccia, MD, Gabriella Fontanini, MD, Maria Elena Filice, MD, and Luca Muscatello, MD


Clear cell adenocarcinoma is an extremely rare tumor of the head and neck region. We report a case of a 75-year-old Caucasian woman with a 10-day history of hemoptysis but with no pain or other significant symptoms. A head and neck computed tomography scan with contrast medium...

Rectal adenocarcinoma metastatic to the larynx

April 1, 2011  |  Joseph Q. Ta, MD and John Y. Kim, MD


Malignancies metastatic to the larynx are rare, accounting for fewer than 1% of all laryngeal cancers with metastatic sources; the most common of these metastases are cutaneous melanomas and renal cell carcinomas. Only 13 cases of colon cancer and 2 cases of rectal...

Papillary cystadenocarcinoma originating from a minor salivary gland with lymph node metastases

March 1, 2011  |  Demet Etit, MD, Nese Ekinci, MD, Gozde Evcim, MD, and Kazim Onal, MD


Papillary cystadenocarcinoma is a rare malignant neoplasm of the salivary glands. This tumor most commonly arises in the major salivary glands, mainly in the parotid gland, and rarely metastasizes to regional lymph nodes. We report here a case of papillary cystadenocarcinoma...

Tonsillar metastasis of signet-ring cell adenocarcinoma of the colon

August 1, 2010  |  Kelly K. Park, MD and Youn W. Park, MD, FACS


Cases of primary colorectal signet-ring cell carcinoma metastatic to the tonsil are extremely rare. To the best of our knowledge, only 4 such cases have been previously reported in the literature. We report a new case in a 76-year-old white woman. She was treated with...


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