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Amyloidosis: A rare case with nodular lesions on the tongue and buccal mucosa

October 24, 2013  |  Evren Erkul, MD; Hakan Cincik, MD

The pathogenesis of amyloidosis appears to be multifactorial, but the common final pathway is identical in all forms of the disease; i.e., the production of amyloid fibrils in the extracellular matrix.

Oral hairy leukoplakia in an HIV- negative patient

June 12, 2013  |  Evan M. Graboyes, MD; Clint T. Allen, MD; Rebecca D. Chernock, MD; and Jason A. Diaz, MD


We report the case of a 31-year-old woman with systemic lupus erythematosus who was found to have oral hairy leukoplakia (OHL). She was on immunosuppressive therapy but was human immunodeficiency virus (HIV)-negative. OHL has been previously reported in HIV-negative patients...

Intramuscular lipoma of the tongue masquerading as angioedema

January 24, 2013  |  Ali Amirzadeh, MD; William Klaustermeyer, MD


In most cases, the diagnostic evaluation of angioedema is challenging, as there are many possible etiologies. We report a case of an infiltrating lipoma of the tongue that masqueraded as angioedema. The patient, a 68-year-old man, presented with tongue swelling that had...

Development of hemangioma in a tongue harboring long-standing angiokeratoma circumscriptum

November 1, 2012  |  J. Madana, MS, DNB; Deeke Yolmo, MS; S. Gopalakrishnan, MS; Sunil Kumar Saxena, MS


Angiokeratoma is a very rare vascular lesion of the papillary dermis. It is characterized by vascular ectasia with overlying epidermal hyperkeratosis. The systemic form of angiokeratoma is associated with Fabry disease and fucosidosis. There are several localized forms. Tongue...

Hypoglossal nerve tumor: A rare primary extracranial meningioma of the neck

November 1, 2012  |  Abu Bakar Zulkiflee, MS; Narayanan Prepageran, FRCS; Omar Rahmat, MS; Pailoor Jayalaskhmi, MPath, FRCPath; Tengku Sharizal, MS


We report a case of primary extracranial meningioma arising from the hypoglossal nerve in a 54-year-old man who presented with a 9-month history of hoarseness and progressive dysphagia. He had also noticed that his tongue was deviated to the left and, as a result, he was having...

Bipolar radiofrequency-induced interstitial thermoablation for oral cavity vascular malformations: Preliminary results in a series of 5 children

November 1, 2012  |  Senol Civelek, MD; Ibrahim Sayin, MD; Ibrahim Ercan, MD; Burak Omur Cakir, MD; Suat Turgut, MD


We report our assessment of the effectiveness of bipolar radiofrequency-induced interstitial thermoablation (BRIT) for the treatment of certain oral cavity vascular malformations in 5 children. Two of these patients had lymphangiomatous macroglossia (LM), 1 had lymphangioma...

A comparison of unilevel and multilevel surgery in obstructive sleep apnea syndrome

August 10, 2012  |  Ümit Tunçel, MD; Hasan Mete İnançlı, MD; Şefik Sinan Kürkçüoğlu, MD; Murat Enoz, MD


We conducted a retrospective study of 35 adults who had undergone tongue base suspension in addition to other surgery for the treatment of obstructive sleep apnea syndrome (OSAS). Our goal was to determine the most effective surgical approach by comparing...

Primary solitary extramedullary plasmacytoma of the tongue

July 5, 2012  |  Cem Onal, MD; Ezgi Oymak, MD; Aysun Uguz, MD; Melek Ergin, MD


Extramedullary plasmacytomas are rare malignancies. Most cases (80%) are seen in the head and neck region, where they represent 1% of all head and neck malignancies. We report a case of an extramedullary plasmacytoma of the tongue that was treated...

Subglottic thyroglossal duct cyst: A rare intralaryngeal presentation

July 5, 2012  |  Regi Kurien, MS; Rajiv Michael, MS, DLO


Thyroglossal duct cysts are common midline neck swellings that can present at any site along their migratory pathway. They are frequently situated just below the hyoid bone. Extension to the subglottic area is very rare; such an unusual presentation can...

Primary extranodal T-cell non-Hodgkin lymphoma of the tongue

January 25, 2012  |  J. Madana, MS, DNB, Deeke Yolmo, MS, Sunil Kumar Saxena, MS, and S. Gopalakrishnan, MS


The most common sites of extranodal non-Hodgkin lymphoma (NHL) are the gastrointestinal tract and the head and neck region. Head and neck involvement accounts for 8 to 13% of all extranodal lymphomas. Primary NHLs of the oral cavity, especially in the tongue, are extremely rare...

Orofaciodigital syndrome

January 25, 2012  |  Baris Naiboglu, MD, Cagatay Oysu, MD, and Tanju Gokceer, MD


Orofaciodigital syndrome is a very rare entity with X-linked dominant inheritance characterized by oral, facial, and digital anomalies. Thirteen different types have been described in the literature to date. Of these, orofaciodigital syndrome type I has the highest incidence....

Glossal abscess as a complication of tongue-base suspension surgery

December 15, 2011  |  Bobby A. Tajudeen, MD, Biana G. Lanson, MD, and Pamela C. Roehm, MD, PhD


Approximately 60 cases of tongue abscess have been reported in the English-language literature over the past 30 years. We report what we believe is the first case of a glossal abscess that arose as a complication of tongue-base suspension surgery. The patient was a 31-year-old...


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