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Salivary epidermal growth factor concentrations in patients with Sjogren syndrome and laryngopharyngeal reflux

June 20, 2017  |  Claudia A. Eckley, MD; Marco Antônio dos Anjos Corvo, MD; Luis Roberto Sardinha, PhD; Bianca Liquidato, MD; Luiz Vicente Rizzo, MD

Abstract

Sjögren syndrome was chosen as a clinical model to study acinar salivary deficiencies in the development of laryngopharyngeal reflux (LPR). The objective of this prospective cohort study was to compare salivary epidermal growth factor (EGF) concentrations of patients with...

Submandibular salivary gland tumors: Clinical course and outcome of a 20-year multicenter study

March 24, 2017  |  Aviram Mizrachi, MD; Gideon Bachar, MD; Yaron Unger, MD; Ohad Hilly, MD; Dan M. Fliss, MD; Thomas Shpitzer, MD

Abstract

The purpose of this retrospective chart review study was to review the nature and clinical course of benign and malignant submandibular gland tumors at 2 major university-affiliated tertiary medical centers. All patients who underwent submandibular salivary gland excision...

The rising incidence of major salivary gland cancer in the United States

March 24, 2017  |  Anthony G. Del Signore, MD; Uchechukwu C. Megwalu, MD

Abstract

We performed a population-based historical cohort study using the Surveillance, Epidemiology, and End Results (SEER) database to determine trends in the incidence of major salivary gland cancer and to evaluate the effect of sex, tumor size, histology, primary site, and extent...

Secretory carcinoma

December 7, 2016  |  Lester D. Thompson, MD

This tumor presents as a solitary, circumscribed but not encapsulated mass, although it may have invasive borders.

Primary salivary duct carcinoma arising from the Stensen duct

September 19, 2016  |  Kenji Noda, MD; Takashi Hirano, MD, PhD; Tomoyo Okamoto, MD; Masashi Suzuki, MD, PhD

Abstract

This report describes a salivary duct carcinoma (SDC) arising from the extraglandular portion of the Stensen duct. The patient was a 56-year-old man who presented with a palpable, elastic, hard mass without tenderness in the right cheek. Computed tomography revealed a tumor of...

Ultrasonography-guided minimally invasive removal of parotid calculi: A prudent approach

February 24, 2016  |  Uma Patnaik, MS, DNB; Sreejith Nair, MS; Atul Mishra, MD

Abstract

The trend in modern salivary calculi surgery is toward minimally invasive procedures because these benign conditions do not warrant open salivary gland surgery. Since ultrasonography is readily available, highly specific, noninvasive, and cost-effective, we have used an...

An unusual tongue base mass in an infant: Tongue base sialolipoma

December 14, 2015  |  Dawn T. Teo, MBBS; Romaine F. Johnson, MD, MPH; John E. McClay, MD

Abstract

Sialolipoma is a rare tumor that occurs in the head and neck. We present a case arising from a minor salivary gland in an infant. The 6-month-old infant presented with difficulty swallowing, frequent reflux, and snoring that had been worsening several weeks before presentation...

Submandibular gland megalith eroding the floor of the mouth: A case report

December 20, 2013  |  Sourav Singh, MDS; Smita Singh, MDS

Abstract

Sialolithiasis is the most common pathologic condition affecting the salivary glands. However, large sialoliths (megaliths) are considered rare. The submandibular glands are more susceptible to stone formation than are the other salivary glands. We describe the case of a 55-...

Mucocele: Retention and extravasation types

March 25, 2013  |  Lester D.R. Thompson, MD

The extravasation type is the most common mucocele, more common in children and young adults, with a peak in the second decade of life.

Massive calcification in a pleomorphic adenoma: Report of an unusual presentation

January 24, 2013  |  Luiz O.M. Coelho, MD; Sergio E. Ono, MD; Arnolfo de Carvalho Neto, PhD; Christiane S. Kawasaki, MD; Luciano V. Sabóia, MD; Maria F. Soares, MD

Abstract

We report a case of histology-proven pleomorphic adenoma of the parapharyngeal space in a 20-year-old man. This case was unusual in that a massive amount of dystrophic calcification was scattered throughout the tumor. The patient underwent successful surgical resection, and he...

Salivary duct carcinoma

September 7, 2012  |  Lester D.R. Thompson, MD

A case of a giant submandibular gland calculus perforating the floor of the mouth

June 4, 2012  |  Raffaele Rauso, MD; Giulio Gherardini, MD, PhD; Paolo Biondi, MD; Gianpaolo Tartaro, MD; Giuseppe Colella, MD, DDS

Abstract

Sialolithiasis is characterized by the obstruction of salivary gland secretion by a calculus. It is associated with swelling, pain, and infection of the affected gland. More than 80% of all salivary calculi occur in the...

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