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Effect of a corticosteroid (triamcinolone) and chlorhexidine on chemotherapy-induced oxidative stress in the buccal mucosa of rats

December 7, 2016  |  Sami Gümüş, MD; Murat Yarıktaş, MD; Mustafa Nazıroğlu, PhD; Abdülhadi Cihangir Uğuz, PhD; Giray Aynali, MD; Şirin Başpınar, MD

Abstract

Oral mucositis manifests as erythematous and ulcerative lesions of the oral mucosa. Among its various causes, cancer treatment (e.g., chemotherapy with or without radiation therapy) is one of the more well known. It has been widely mentioned that oxidative stress parameters...

Secretory carcinoma

December 7, 2016  |  Lester D. Thompson, MD

This tumor presents as a solitary, circumscribed but not encapsulated mass, although it may have invasive borders.

Nasopharyngeal airway to prevent tension pneumocephalus after open resection of anterior skull base tumors

December 7, 2016  |  Matthew E. Spector, MD; Jon-Paul Pepper, MD; Stephen Sullivan, MD; Lawrence Marentette, MD; Erin McKean, MD

Abstract

We conducted a retrospective study to assess the efficacy of using a nasopharyngeal airway in lieu of a tracheotomy or prolonged intubation for the diversion of airflow to prevent tension pneumocephalus after an open resection of anterior skull base tumors. Our study population...

Risk of thyroid malignancy following an index head and neck squamous cell carcinoma: A population-based study

December 7, 2016  |  Jason Y. Chan, MBBS; Zhen Gooi, MBBS; Wojciech K. Mydlarz, MD; Nishant Agrawal, MD

Abstract

To evaluate the incidence of a subsequent primary thyroid malignancy in patients with an index head and neck squamous cell carcinoma (HNSCC), we analyzed the National Cancer Institute's Surveillance, Epidemiology, and End Results database to identify a cohort of patients who...

Facial reanimation according to the postresection defect during lateral skull base surgery

December 7, 2016  |  John P. Leonetti, MD; Sahar Nadimi, MD; Sam J. Marzo, MD; Douglas Anderson, MD; Darl Vandevender, MD

Abstract

The vast majority of benign tumors of the cerebellopontine angle, temporal bone, and parotid gland can be successfully resected without permanent injury to the facial nerve. Malignant tumors or recurrent disease may require facial nerve sacrifice, especially if preoperative...

Sclerotic effect of oxytetracycline on the submandibular gland: An experimental model

December 7, 2016  |  Oguz Guclu, MD; Asli Muratli, MD; Deniz Arik, MD; Kazim Tekin, MD; Halil Erdogan, MD; Fevzi Sefa Derekoy, MD

Abstract

Oxytetracycline has been suggested as an alternate therapy for chronic recurrent sialadenitis and sialorrhea. We conducted an experimental study to investigate the sclerotic effect of this drug on the submandibular gland by histopathologic methods. Our subjects were 20 New...

End-of-life decision making in geriatric terminal head and neck cancer

December 7, 2016  |  Kourosh Parham, MD, PhD, FACS; Karen M. Kost, MD, FRCSC

In the oncogeriatric setting, the comprehensive geriatric assessment has been recognized as providing useful information supplementary to what can be obtained via standard oncology status assessments.

Cutaneous angiosarcoma of the scalp mimicking facial cellulitis

October 25, 2016  |  Sheng-Chiao Lin, MD; Ting-Shou Chang, MD

On first appearance, angiosarcomas can be mistaken for benign lesions, such as cellulitis, hemangioma, rosacea, and rhinophyma.

Cervical metastasis in squamous cell carcinoma of the hard palate and maxillary alveolus

October 25, 2016  |  Yekaterina Koshkareva, MD; Jeffrey C. Liu, MD; Miriam Lango, MD; Thomas Galloway, MD; John P. Gaughan, PhD; John A. Ridge, MD, PhD

Abstract

We conducted a retrospective study to determine the incidence and treatment outcomes of neck metastases in patients with squamous cell carcinoma (SCC) of the hard palate and/or maxillary alveolus after surgical excision of the primary tumor. We also sought to identify any risk...

Prognostic factors in metastatic cutaneous squamous cell carcinoma of the head and neck

October 25, 2016  |  Gideon Bachar, MD; Aviram Mizrachi, MD; Naomi Rabinovics, MD; Dan Guttman, MD; Thomas Shpitzer, MD; Dean Ad-El, MD; Tuvia Hadar, MD

Abstract

Metastatic cutaneous squamous cell carcinoma (SCC) of the head and neck poses a significant therapeutic challenge due to its aggressive biologic behavior. We conducted a retrospective study of 71 patients-58 men and 13 women, aged 28 to 88 years (mean: 71)-who had been treated...

Breast cancer metastasis to the thyroid gland

October 25, 2016  |  Michael Goldenberg, MA; Joshua Warrick, MD; Mariano Russo, BS; Darrin V. Bann, MD, PhD

It is important to distinguish between metastatic disease and a second primary thyroid malignancy, which is more common than thyroid gland metastasis.

Primary salivary duct carcinoma arising from the Stensen duct

September 19, 2016  |  Kenji Noda, MD; Takashi Hirano, MD, PhD; Tomoyo Okamoto, MD; Masashi Suzuki, MD, PhD

Abstract

This report describes a salivary duct carcinoma (SDC) arising from the extraglandular portion of the Stensen duct. The patient was a 56-year-old man who presented with a palpable, elastic, hard mass without tenderness in the right cheek. Computed tomography revealed a tumor of...