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Rhinology

The role of MMP-2, MMP-9, and TIMP-1 in the pathogenesis of nasal polyps: Immunohistochemical assessment at eight different levels in the epithelial, subepithelial, and deep layers of the mucosa

April 28, 2015  |  Nuray Bayar Muluk, MD; Osman Kürşat Arikan, MD; Pınar Atasoy, MD; Rahmi Kiliç, MD; Eda Tuna Yalçinozan, MD

Abstract

We conducted a prospective study to investigate the role of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the pathogenesis of nasal polyps. Our study group consisted of 24 patients-21 men and 3...

Sinonasal undifferentiated carcinoma as a third primary neoplasm: A case report and review of the literature

April 28, 2015  |  John J. Chi, MD; Michael D. Feldman, MD; James N. Palmer, MD

Abstract

A 71-year-old man with a history of a pituitary prolactinoma and metastatic pancreatic carcinoma presented with epistaxis, visual changes, bilateral ophthalmoplegia, involuntary closure of the left eye, and ptosis of the right eye. The patient was found to have a soft-tissue...

Prophylactic antibiotic therapy for fractures of the maxillary sinus

April 28, 2015  |  Robert S. Schmidt, MD; Kelley M. Dodson, MD; Richard A. Goldman, MD

Abstract

We conducted a study to examine the incidence of acute sinusitis following maxillary sinus fractures, as well as the impact of antibiotics in the postinjury period. Fifty patients who presented to our institution with a fracture of the maxillary sinus were prospectively...

Maxillary sinus cyst containing a bone chip

March 2, 2015  |  Jae-Hoon Lee, MD

If bone fragments in the sinus can be removed, the patient's prognosis is usually excellent.

Septic arthritis: A unique complication of nasal septal abscess

March 2, 2015  |  Steven M. Olsen, MD; Cody A. Koch, MD, PhD; Dale C. Ekbom, MD

Abstract

Nasal septal abscesses (NSAs) occur between the muco-perichondrium and the nasal septum. They most often arise when an untreated septal hematoma becomes infected. The most commonly reported sequela is a loss of septal cartilage support, which can result in a nasal deformity....

Endoscopic view of a medial ethmoid drainage pathway into the middle meatus

February 2, 2015  |  Dewey A. Christmas, MD; Joseph P. Mirante, MD, FACS; Eiji Yanagisawa, MD, FACS

The ostium of the ethmoid bulla is often found in the hiatus semilunaris superior, but that it can also be found in the anterior or lateral wall of the bulla, the ethmoid infundibulum, the hiatus semilunaris inferior, or the retrobullar recess.

Primary thyroid-like papillary adenocarcinoma of the nasal septum: A case report

February 2, 2015  |  Kerem Ozturk, MD; Rasit Midilli, MD; Ali Veral, MD; Yesim Ertan, MD; Bulent Karci, MD

Abstract

Primary thyroid-like papillary adenocarcinomas are extremely rare neoplasms that generally originate in the nasopharynx. We report the case of a 24-year-old woman who was diagnosed with a thyroid-like papillary adenocarcinoma that originated in the nasal septum. The tumor was...

Palliative endoscopic surgery for sinonasal metastases: A case report and literature review

February 2, 2015  |  Jason M. Roberts, MD; Christopher Brook, MD; Steven Parnes, MD

Abstract

Cancer metastatic to the paranasal sinuses often presents with ophthalmologic and facial deformities, as well as sinonasal complaints. These diminutive tumors are difficult to effectively treat, often leading to poor quality of life. Although breast cancer is a common cancer...

Effects of nasal saline lavage on pediatric sinusitis symptoms and disease-specific quality of life: A case series of 10 patients

February 2, 2015  |  Sandra Y. Lin, MD; Katherine M. Baugher, DO; David J. Brown, MD; Stacey L. Ishman, MD

Abstract

We conducted a prospective study to assess (1) the effects of daily nasal irrigation in children with chronic sinonasal symptoms and (2) the impact that treatment had on disease-specific quality of life as assessed by a validated instrument, the five-item Sinus and Nasal...

Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review

February 2, 2015  |  Boon Ping Toe, FRCR(Lond); Norlisah Ramli, FRCR(Lond); Sze Yin Lam, MRad(Mal); Kum Thong Wong, FRCPath(Lond); Narayanan Prepageran, FRCS(Edin)

Abstract

Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma. To date, only 95 cases of sinonasal BSCC have been reported in the English-language literature, and they account for 5% of all cases of head and neck BSCC. We describe what we believe is only...

Endoscopic view of nasopharyngeal scarring

January 19, 2015  |  Joseph P. Mirante, MD, FACS; Dewey A. Christmas, MD; Eiji Yanagisawa, MD, FACS

A finding of fibrous or scar tissue in the nasopharynx usually indicates previous trauma or surgery in the area. The most common iatrogenic cause is adenoidectomy.

An uncommon cause of allergic fungal sinusitis: Rhizopus oryzae

January 19, 2015  |  Marie Devars du Mayne, MD; Maxime Gratacap, MD; David Malinvaud, MD, PhD; Frederic Grenouillet, PhD; Pierre Bonfils, MD, PhD

Abstract

We report what we believe is the first case of allergic fungal rhinosinusitis (AFRS) caused by the fungus Rhizopus oryzae. Our patient was a 32-year-old woman who presented with unilateral nasal polyps and chronic nasal dysfunction. Computed tomography of the sinuses...

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