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Hemorrhagic polyp with large occult sulcus vocalis in a singer

September 19, 2016  |  Meghan O'Brien, DO; Libby J. Smith, DO

A sulcus can decrease the functional vibratory property of the vocal fold free edge and result in dysphonia.

Postoperative hypofunctioning of the thyroid gland after total laryngectomy

August 21, 2016  |  Sirshak Dutta, MS, DLO; Kaustuv Das Biswas, MS, DLO; Soumya Ghatak, MS; Dibakar Haldar, MD; Indranil Sen, MS; Ramanuj Sinha, MS, DNB


Primary laryngeal carcinoma is a common cancer, predominantly affecting males. Hypothyroidism is an undesirable sequela of both surgery and radiotherapy, the two most commonly used modalities of treatment. For advanced cases, standard treatment protocol includes total...

Vocal fold granulomas

August 21, 2016  |  Helen Lesser, BS; Amy Rutt, DO; Robert T. Sataloff, MD, DMA, FACS

Occasionally, even after excellent reflux control, surgical removal and steroid injection into the base of the granulomas, application of mitomycin C, and voice therapy, patients develop recurrent granulomas.

Hypopharyngeal strictures and webs

August 21, 2016  |  Mark A. Fritz, MD; Gregory N. Postma, MD

These thin, web-like narrowings can often be missed or underappreciated on contrast swallows yet can be markedly symptomatic.

Neuroendocrine tumors of the larynx

July 18, 2016  |  Lester D. Thompson, MD

The most common laryngeal neuroendocrine tumor is the atypical carcinoid (moderately differentiated neuroendocrine carcinoma), which is a malignant epithelial tumor showing neuroendocrine histologic and immunohistochemical features.

Patient preferences in early glottic cancer treatment

July 18, 2016  |  Michael L. McNeil, MD; Derek R. Wilke, MD, FRCP(C); S. Mark Taylor, MD, FRCS(C), FACS


Patients with early-stage glottic cancer are primarily treated with one of three options: endoscopic laser excision, external-beam radiation, or open conservation surgery. We sought to determine patient preferences for treatment when presented with a choice between CO2 laser...

Laryngeal amyloidosis

July 18, 2016  |  Karthik S. Shastri, MD; Amy L. Rutt, DO; Robert T. Sataloff, MD, DMA, FACS

The diagnosis of laryngeal amyloidosis should trigger evaluation for systemic amyloidosis.

Lingual osseous choristoma

July 18, 2016  |  Daniel T. Ginat, MD, MS; Louis Portugal, MD

When they occur, symptoms of lingual osseous choristomas may include globus sensation, dysphagia, gagging, nausea, and irritation.

Dietary consumption patterns and laryngeal cancer risk

June 14, 2016  |  Petros V. Vlastarakos, MD, MSc, PhD; Andrianna Vassileiou, MD, PhD; Evie Delicha, MSc; Dimitrios Kikidis, MD, MSc; Dimosthenis Protopapas, MD, PhD; Thomas P. Nikolopoulos, MD, DM, PhD


We conducted a case-control study to investigate the effect of diet on laryngeal carcinogenesis. Our study population was made up of 140 participants-70 patients with laryngeal cancer (LC) and 70 controls with a non-neoplastic condition that was unrelated to diet, smoking, or...

Asymptomatic medial vocal fold hemorrhagic polyp

June 14, 2016  |  Ozlem E. Kantarcioglu, MD; Amy L. Rutt, DO; Robert T. Sataloff, MD, DMA, FACS

This patient did not realize that her voice was pathologic until after she had been treated.

Coexistent chronic myelogenous leukemia with squamous cell carcinoma of the larynx associated with NOD2/CARD15 mutation in a young adult

June 14, 2016  |  Marcin Fraczek, MD; Agnieszka Stembalska, MD; Pawel Karpinski, MD; Tomasz Krecicki, MD


We report the case of a 37-year-old man with human papillomavirus-positive squamous cell carcinoma of the larynx coexisting with chronic myelogenous leukemia. The patient had no history of smoking or alcohol consumption. Within a few months, his rapidly growing tumor was...

p53 codon 72 polymorphism and its overexpression in patients with laryngeal carcinoma: Prognostic implications

June 14, 2016  |  Gopika Kalsotra, MD; Ashok K. Gupta, MD; Rijuneeta Gupta, MD; Ritu Rathi, PhD; Rajender Prasad, PhD


Abnormalities in the p53 gene are the most common genetic alterations seen in laryngeal carcinoma. No data exist regarding the association between laryngeal carcinoma and a distinct codon 72 variant and its expression. We conducted a prospective study (1) to analyze the p53...


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