Intratympanic membrane congenital cholesteatoma

July 20, 2015     Hiroshi Sakaida, MD, PhD; Kazuhiko Takeuchi, MD, PhD

Cholesteatoma should be differentiated from other conditions with similar otoscopic findings, such as myringosclerosis.

Dehiscent high jugular bulb attached to the tympanic membrane

June 4, 2015     Hiroshi Sakaida, MD, PhD; Kazuhiko Takeuchi, MD, PhD

The differential diagnosis of high jugular bulb includes cholesterol granuloma, aberrant carotid artery, and tumors such as paraganglioma or schwannoma.

Bezold abscess

June 4, 2015     Yu-Hsuan Lin, MD; Ming-Yee Lin, MD

In some circumstances, the only sign or symptom of Bezold abscess is an unnoticed neck lump.

Bilateral keratin horns arising from the tympanic membranes: A case report

February 2, 2015     Chu Qin Phua, MRCS, DOHNS; Vikas Malik, FRCS(ORL-HNS); Patrick Zaid Sheehan, FRCS(ORL)


A keratin horn is a horn-like projection composed of dense keratotic material. It usually arises in sun-exposed areas of the body. It can be derived from a variety of underlying benign, premalignant, or malignant epidermal lesions. Risk factors associated with malignant change within a keratin horn include a wide base, male sex, and increasing age, in addition to an origin in a sun-exposed area. The mainstay of management is to obtain a biopsy from the base of the horn and subsequent excision if the histopathologic analysis suggests a malignancy. We report an extremely rare case of bilateral keratin horns arising from the tympanic membranes in a 64-year-old woman. To the best of our knowledge, this is the first report of its kind to be published in the English-language literature.

Tympanic membrane perforation with squamous epithelial ingrowth

August 27, 2014     Danielle M. Blake, BA; Alejandro Vazquez, MD; Senja Tomovic, MD; Robert W. Jyung, MD

The squamous epithelium of the tympanic membrane and external auditory canal exhibits an inherent migration pattern to facilitate the exfoliation of keratinizing squamous cells as part of a natural cleansing mechanism.

Tympanic paraganglioma

May 7, 2014     Danielle M. Blake, BA; Senja Tomovic, MD; Robert W. Jyung, MD

Patients classically present with pulsatile tinnitus and a red mass medial to the tympanic membrane. Some patients may have findings of a red mass that blanches with pneumatic otoscopy, called Brown's sign.

Eosinophilic otitis media

February 12, 2014     Alejandro Vazquez, MD; Danielle M. Blake, BA; and Robert W. Jyung, MD

Eosinophilic otitis media is refractory to conventional therapy for otitis media and may lead to severe hearing impairment if not recognized promptly.

Extrusion of hydroxyapatite ossicular prosthesis

October 23, 2013     Danielle M. Blake, BA; Senja Tomovic, MD; Robert W. Jyung, MD

Extrusion of hydroxyapatite prostheses is unfortunately a common complication of middle ear surgery.

Degraded tympanostomy tube in the middle ear

July 21, 2013     Nitin J. Patel, MD; Joshua Bedwell, MD; Nancy Bauman, MD; Brian K. Reilly, MD

Tympanostomy tubes can cause a foreign-body reaction that can lead to myringitis and the development of granulation tissue and polyps.

Middle ear metastasis from dormant breast cancer as the initial sign of disseminated disease 20 years after quadrantectomy

March 24, 2013     Teresa Pusiol, MD; Ilaria Franceschetti, MD; Francesca Bonfioli, MD; Francesco Barberini, MD; Giovanni Battista Scalera, MD; Irene Piscioli, MD


We describe an unusual case of breast cancer metastatic to the middle ear in a 71-year-old woman. The metastasis was the initial sign of disseminated disease 20 years after the patient had undergone a quadrantectomy for her primary disease. Computed tomography (CT) demonstrated the presence of an intratympanic mass with a soft-tissue density that was suggestive of chronic inflammation. The patient underwent a canal-wall-down tympanoplasty. When a brownish mass was found around the ossicles, a mastoidectomy with posterior tympanotomy was carried out. However, exposure of the tumor was insufficient, and therefore the posterior wall of the ear canal had to be removed en bloc. Some tumor was left on the round window membrane so that we would not leave the patient with a total hearing loss. Our case highlights the limitations of CT and magnetic resonance imaging in differentiating inflammatory and neoplastic lesions.

An extruded ossicular prosthesis

February 25, 2013     Willis S.S. Tsang, FRCSEd(ORL); Michael C.F. Tong, MD(CUHK); C. Andrew van Hasselt, M Med(Otol)

Extrusion of ossicular prostheses results from postoperative tympanic membrane medialization. The incorporation of cartilage grafting material is recommended to minimize extrusion.

Intraoperative view of a glomus tympanicum

December 31, 2012     Waitsz T. Chang, MRCS; Willis S.S. Tsang, FRCSEd(ORL)

For the treatment of a small glomus tympanicum, surgical excision via an anterior tympanotomy approach is possible.

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