Although obstruction of the nasolacrimal duct is a fairly common finding in newborns, development of a dacryocystocele (nasolacrimal duct cyst) is uncommon. Bilateral dacryocystoceles that expand intranasally and cause respiratory distress in the newborn are rarer still. We present 2 cases of bilateral dacryocystoceles that caused neonatal respiratory compromise. Our first patient, a newborn girl, was managed successfully with probing of the nasolacrimal ducts and endoscopic marsupialization of the cysts. Our second patient, a newborn boy, responded well to conservative treatment with a nasal decongestant, lacrimal sac massage, and warm compresses. While bilateral dacryocystoceles are rare, they should be considered in cases of neonatal respiratory distress and concomitant nasal obstruction.