Larynx

Papillary squamous cell carcinoma of the larynx

August 15, 2011     Candice Colby, MD and Adam M. Klein, MD
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Abstract

Papillary squamous cell carcinoma is a rare variant of squamous cell carcinoma of the aerodigestive tract that has been correlated with a more favorable prognosis than conventional squamous cell carcinoma of the head and neck. In this report, the authors present a case of papillary squamous cell carcinoma and a review of the literature on this topic.

Pathologic evaluation of primary laryngeal anterior commissure carcinoma both in patients who have undergone open surgery as initial treatment and in those who have undergone salvage surgery after irradiation failure

April 30, 2011     Wael A. Ahmed, MD, MSc, Kenji Suzuki, MD, PhD, Yoshimune Horibe, MD, PhD, Ichiro Kato, MD, Toshiyuki Fujisawa, MD, and Yoichi Nishimura, MD
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Abstract

Laryngeal anterior commissure (AC) cancer has been the subject of much controversy. Our study was aimed at pathologically evaluating the tendency of AC cancer to invade the thyroid cartilage and analyzing the role of thyroid cartilage invasion by tumor cells at the AC as an anatomic cause for irradiation failure. Our study included 36 patients with glottic cancer involving AC. Patients with recurrent or persistent disease after radiotherapy underwent salvage surgery. Surgical specimens from 22 patients who had open surgery, either as primary or salvage surgery, were available for pathologic examination to identify the presence of cartilage invasion. We found microscopic invasion of the thyroid cartilage in 40.9% of the studied tumors. Only 21.4% of patients who had open salvage surgery showed evidence of cartilage invasion at the AC. We concluded that laryngeal AC cancers are more likely to invade the cartilage, and that anatomic risk factors are not the main cause of irradiation failure.

Extraskeletal giant cell tumor of the larynx: Case report and review of the literature

April 30, 2011     Mana Rochanawutanon, MD, Phurich Praneetvatakul, MD, Jiraporn Laothamatas, MD, and Vorachai Sirikulchayanonta, MD
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Abstract

Giant cell tumors of the larynx typically arise within the laryngeal skeleton. We report a case of a laryngeal tumor in a 29-year-old man that clearly originated outside the laryngeal cartilage. It was identified as a soft-tissue giant cell tumor. To the best of our knowledge, an extraskeletal laryngeal giant cell tumor has not been previously reported.

Laryngeal spindle cell squamous cell carcinoma

April 30, 2011     Lester D.R. Thompson, MD
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An uncommon case of laryngeal oncocytoma

April 30, 2011     Brett Travis, MD, Enrique Palacios, MD, FACR, and Curt L. McCarty, MD
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Rectal adenocarcinoma metastatic to the larynx

March 31, 2011     Joseph Q. Ta, MD and John Y. Kim, MD
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Abstract

Malignancies metastatic to the larynx are rare, accounting for fewer than 1% of all laryngeal cancers with metastatic sources; the most common of these metastases are cutaneous melanomas and renal cell carcinomas. Only 13 cases of colon cancer and 2 cases of rectal adenocarcinoma metastatic to the larynx have been previously reported in the literature. We report a new case of rectal adenocarcinoma metastatic to the larynx that resulted in subglottic stenosis in a 60-year-old man. We also review the literature, and we discuss the presentations of and treatments for this rare entity.

Laryngeal Teflon granuloma: Endoscopy, laryngeal videostroboscopy, and CT imaging

March 1, 2011     Carlos M. Rivera-Serrano, MD and Libby J. Smith, DO
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Proton pump inhibitors: Adverse effects

December 17, 2010     Robert T. Sataloff, MD, DMA, FACS, Editor-in-Chief
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Most otolaryngologists are now aware of the importance and high incidence of laryngopharyngeal reflux (LPR), especially in patients with voice complaints. Although many controversies remain regarding optimal diagnosis and treatment, long-term therapy with acid suppression is used commonly.

Laryngeal paraganglioma: Report of an unusual entity

October 31, 2010     Asim Kaytaz, MD, Emin Karaman, MD, Deniz Tuna Edizer, MD, Yusuf Haciyev, MD, and Buge Oz, MD
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Abstract

Paragangliomas are rare in the larynx. When they do occur there, the most common subsite is the supraglottic compartment. Unlike other neuroendocrine tumors of the larynx, laryngeal paragangliomas are three times as common in women as in men. Although a preoperative biopsy is often performed to establish the diagnosis, this procedure carries a considerable risk of bleeding, which may necessitate a tracheotomy to secure the airway. Immunohistochemical staining is useful in the differential diagnosis to distinguish a paraganglioma from other neuroendocrine tumors. Computed tomography and/or magnetic resonance imaging with preoperative angiography and possible embolization are important to obtain prior to treatment. Surgical excision is the treatment of choice.

Laryngeal candidiasis

October 31, 2010     Venu Divi, MD, Reena Gupta, MD, Robert T. Sataloff, MD, DMA, FACS, and Parmis Pebdani, DO
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Laryngeal paraganglioma

September 30, 2010     Yoav Hahn, MD, Richard Isaacs, MD, and Peter C. Belafsky, MD, PhD
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Seldinger technique for in-office tracheoesophageal puncture

July 31, 2010     Jacqui Allen, MBChB, FRACS and Peter C. Belafsky, MD, PhD
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