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Larynx

Coexistent chronic myelogenous leukemia with squamous cell carcinoma of the larynx associated with NOD2/CARD15 mutation in a young adult

June 14, 2016  |  Marcin Fraczek, MD; Agnieszka Stembalska, MD; Pawel Karpinski, MD; Tomasz Krecicki, MD

Abstract

We report the case of a 37-year-old man with human papillomavirus-positive squamous cell carcinoma of the larynx coexisting with chronic myelogenous leukemia. The patient had no history of smoking or alcohol consumption. Within a few months, his rapidly growing tumor was...

p53 codon 72 polymorphism and its overexpression in patients with laryngeal carcinoma: Prognostic implications

June 14, 2016  |  Gopika Kalsotra, MD; Ashok K. Gupta, MD; Rijuneeta Gupta, MD; Ritu Rathi, PhD; Rajender Prasad, PhD

Abstract

Abnormalities in the p53 gene are the most common genetic alterations seen in laryngeal carcinoma. No data exist regarding the association between laryngeal carcinoma and a distinct codon 72 variant and its expression. We conducted a prospective study (1) to analyze the p53...

Dietary consumption patterns and laryngeal cancer risk

June 14, 2016  |  Petros V. Vlastarakos, MD, MSc, PhD; Andrianna Vassileiou, MD, PhD; Evie Delicha, MSc; Dimitrios Kikidis, MD, MSc; Dimosthenis Protopapas, MD, PhD; Thomas P. Nikolopoulos, MD, DM, PhD

Abstract

We conducted a case-control study to investigate the effect of diet on laryngeal carcinogenesis. Our study population was made up of 140 participants-70 patients with laryngeal cancer (LC) and 70 controls with a non-neoplastic condition that was unrelated to diet, smoking, or...

Unconventional fix for an orocutaneous fistula

June 14, 2016  |  Laura Garcia-Rodriguez, MD; Rahil Dharia, BS; Cameron Heilbronn, MD; Tamer Ghanem, MD, PhD

Local risk factors for OCF and PCF secondary to total laryngectomy include infections, exposure of salivary fluids, and radiation.

Primary NK/T-cell lymphoma of the larynx: Report of 2 cases and review of the English-, Japanese-, and Chinese-language literature

April 30, 2016  |  Su-Yu Zhu, MD; Yuan Yuan, MD; Ke Liu, MD, MSc; Liang Zeng, MD, PhD; Ju-Mei Zhou, MD, PhD; Qiong-Hui Lu, MD; Zai-Jie Huang, MD

Abstract

Natural killer/T (NK/T) -cell lymphoma in the larynx is extremely rare, as only 29 cases have been previously reported in the English-language, Japanese-language, and Chinese-language literature. Its characteristics have never been systematically illustrated. We report 2 new...

Thymoma with an incidental benign laryngeal mass mimicking laryngeal carcinoma: Case report

February 24, 2016  |  Gokce Simsek, MD; Istemihan Akin, MD; Cem Saka, MD; Fulya Koybasioglu, MD

Abstract

Thymic carcinomas are rarely seen. Because of recurrent laryngeal nerve involvement, hoarseness is a common presenting symptom. Persistent hoarseness in a male smoker past his fifth decade is also a distinctive symptom for laryngeal carcinoma. Stroboscopic laryngeal examination...

Novel injection technique into the interarytenoid area to treat dysphagia

February 24, 2016  |  Meghan Brooking, DO; Amanda Hu, MD, FRCSC; Robert T. Sataloff, MD, DMA, FACS

Augmentation of the interarytenoid space is a simple and innovative alternative to the traditional paraglottic space injection.

Laryngotracheal mucormycosis: Report of a case

January 22, 2016  |  Jillian Mattioni, DO; Joel E. Portnoy, MD; Jaime Eaglin Moore, MD; David Carlson, DO; Robert T. Sataloff, MD, DMA, FACS

Abstract

Airway mucormycosis is a deadly opportunistic infection that affects immunocompromised persons, particularly diabetics and those undergoing chemotherapy. Although it is typically a pulmonary or sinonasal infection, mucormycosis can affect the larynx and trachea, with...

Globus sensation and laryngopharyngeal reflux

October 31, 2015  |  Michael J. Knabel, BS; Jonathan M. Bock, MD, FACS

Some study results have suggested that psychological factors such as depression and anxiety can influence the etiology of globus.

Laryngeal neuromas in a case of multiple endocrine neoplasia type 2B

October 31, 2015  |  Stanley W. McClurg, MD; Paul E. Wakely Jr., MD; Eugene G. Chio, MD

Abstract

Mucosal neuromas of the larynx in the setting of multiple endocrine neoplasia type 2B (MEN-2B) are extremely rare; to the best of our knowledge, only 2 other cases have been previously reported in the world literature. We describe a new case, which occurred in a 30-year old...

Laryngofissure for resection of a recurrent saccular cyst

October 31, 2015  |  Reed C. Gilbow, BS; J. Mark Reed, MD; Jeffrey D. Carron, MD

Congenital saccular cysts represent a rare cause of airway obstruction and inspiratory stridor in infants.

Laryngeal neurofibroma

October 31, 2015  |  Andreas Anagiotos, MD; Dirk Beutner, MD

Neurofibromas are rarely seen in the larynx. Common symptoms are stridor, hoarseness, dysphagia, dysphonia, and globus sensation.

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