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Larynx

Novel management of an isolated comminuted cricoid cartilage fracture

October 25, 2016  |  Aurora G. Standlee, MD, CPT, MC, USA; Derek J. Rogers, MD, MAJ, MC, USA

Abstract

Laryngeal trauma is a rare occurrence that can result in significant morbidity and mortality. Isolated cricoid cartilage fractures are exceedingly rare, and their treatment is highly variable. We describe a case of an isolated comminuted, uncalcified cricoid cartilage fracture...

Spontaneous laryngeal barotrauma depicted on CT

October 25, 2016  |  Daniel T. Ginat, MD

Laryngeal injuries may result from  external laryngeal trauma or, less often, internal processes such as iatrogenic causes and sneezing with a closed airway.

Clinical course of acute laryngeal hematoma associated with vocal fold fixation

October 25, 2016  |  Wan-Chun Tsai, MD; Jih-Chin Lee, MD; Chih-Hung Wang, MD, PhD; Hsin-Chien Chen, MD, PhD

Disruptions of the anterior commissure, multiple displaced cartilage fractures, and larger open lacerations require open laryngeal exploration.

Features of oral, pharyngeal, and laryngeal lesions in bullous pemphigoid

October 25, 2016  |  Masafumi Ohki, MD; Shigeru Kikuchi, MD, PhD; Atsushi Ohata, MD, PhD; Yuka Baba, MD; Junichi Ishikawa, MD; Hirohito Sugimoto, MD

Abstract

Bullous pemphigoid is an autoimmune bullous disease characterized by skin lesions, with or without oral lesions. The occurrence of pharyngolaryngeal lesions is very rare in affected patients. We conducted a study to investigate the characteristics of oral and pharyngolaryngeal...

Isolated epiglottic lymphatic malformation in a 2-year-old: Diagnosis and treatment

September 19, 2016  |  Tate Naylor, BS; Anthony Sheyn, MD; Felicity Lenes-Voit, MD; Eric Berg, MD

Abstract

Airway obstruction in children has a wide differential diagnosis that includes laryngomalacia, infectious processes, paralysis, extrinsic compression, and other rare anatomic anomalies. Isolated laryngeal lymphatic malformations are rare developments that can manifest with...

Postoperative hypofunctioning of the thyroid gland after total laryngectomy

August 21, 2016  |  Sirshak Dutta, MS, DLO; Kaustuv Das Biswas, MS, DLO; Soumya Ghatak, MS; Dibakar Haldar, MD; Indranil Sen, MS; Ramanuj Sinha, MS, DNB

Abstract

Primary laryngeal carcinoma is a common cancer, predominantly affecting males. Hypothyroidism is an undesirable sequela of both surgery and radiotherapy, the two most commonly used modalities of treatment. For advanced cases, standard treatment protocol includes total...

Patient preferences in early glottic cancer treatment

July 18, 2016  |  Michael L. McNeil, MD; Derek R. Wilke, MD, FRCP(C); S. Mark Taylor, MD, FRCS(C), FACS

Abstract

Patients with early-stage glottic cancer are primarily treated with one of three options: endoscopic laser excision, external-beam radiation, or open conservation surgery. We sought to determine patient preferences for treatment when presented with a choice between CO2 laser...

Neuroendocrine tumors of the larynx

July 18, 2016  |  Lester D. Thompson, MD

The most common laryngeal neuroendocrine tumor is the atypical carcinoid (moderately differentiated neuroendocrine carcinoma), which is a malignant epithelial tumor showing neuroendocrine histologic and immunohistochemical features.

Dietary consumption patterns and laryngeal cancer risk

June 14, 2016  |  Petros V. Vlastarakos, MD, MSc, PhD; Andrianna Vassileiou, MD, PhD; Evie Delicha, MSc; Dimitrios Kikidis, MD, MSc; Dimosthenis Protopapas, MD, PhD; Thomas P. Nikolopoulos, MD, DM, PhD

Abstract

We conducted a case-control study to investigate the effect of diet on laryngeal carcinogenesis. Our study population was made up of 140 participants-70 patients with laryngeal cancer (LC) and 70 controls with a non-neoplastic condition that was unrelated to diet, smoking, or...

Coexistent chronic myelogenous leukemia with squamous cell carcinoma of the larynx associated with NOD2/CARD15 mutation in a young adult

June 14, 2016  |  Marcin Fraczek, MD; Agnieszka Stembalska, MD; Pawel Karpinski, MD; Tomasz Krecicki, MD

Abstract

We report the case of a 37-year-old man with human papillomavirus-positive squamous cell carcinoma of the larynx coexisting with chronic myelogenous leukemia. The patient had no history of smoking or alcohol consumption. Within a few months, his rapidly growing tumor was...

Unconventional fix for an orocutaneous fistula

June 14, 2016  |  Laura Garcia-Rodriguez, MD; Rahil Dharia, BS; Cameron Heilbronn, MD; Tamer Ghanem, MD, PhD

Local risk factors for OCF and PCF secondary to total laryngectomy include infections, exposure of salivary fluids, and radiation.

p53 codon 72 polymorphism and its overexpression in patients with laryngeal carcinoma: Prognostic implications

June 14, 2016  |  Gopika Kalsotra, MD; Ashok K. Gupta, MD; Rijuneeta Gupta, MD; Ritu Rathi, PhD; Rajender Prasad, PhD

Abstract

Abnormalities in the p53 gene are the most common genetic alterations seen in laryngeal carcinoma. No data exist regarding the association between laryngeal carcinoma and a distinct codon 72 variant and its expression. We conducted a prospective study (1) to analyze the p53...

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