Sarcoma

Atypical lipomatous tumor/well-differentiated liposarcoma of the parotid gland: Case report and literature review

September 30, 2009     Usama Mahmood, MD, John D. Nguyen, MD, John Chang, MD, Mai Gu, MD, PhD, and Brian J.F. Wong, MD, PhD
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Abstract

Although liposarcoma is the second most common soft-tissue sarcoma in adults, it is exceedingly rare in the head and neck. According to our MEDLINE search, only 11 cases of liposarcoma of the parotid gland have been reported since 1968. We report a new case of primary atypical lipomatous tumor/well-differentiated liposarcoma of the parotid gland in a 77-year-old man. Because only a very limited number of case reports and small series have been published on liposarcoma in the head and neck, we also provide a review of the literature on this uncommon disease entity.

Chondrosarcoma of the nasal septum

January 1, 2009     Akram Rahal, MD, FRCSC, Joseph R. Durio, PA-C, and Michael L. Hinni, MD
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Abstract

Chondrosarcoma of the nasal septum is a rarely encountered malignancy. When it does occur, early diagnosis is difficult because patients generally present with common, nonspecific sinonasal complaints. We describe a case of chondrosarcoma of the nasal septum in a 38-year-old Hispanic man. The lesion was discovered on computed tomography during a workup for symptoms of chronic sinus disease. The tumor was removed in its entirety and identified as a low-grade lesion that required no further treatment. The patient remained disease-free 4 years postoperatively. We review the diagnosis of this neoplasm and its treatment and follow-up.

Chondrosarcoma of the greater cornu of the hyoid: A case report and literature review

September 25, 2008     Sanjay Verma, MBBCh, MA, FRCS (ORL-HNS), PhD, Perumal Chokkalingam, BSc, FRCS, and Duncan McRae, FRCS, FRCS (ORL-HNS)
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Abstract

We report an unusual case of a young woman with chondrosarcoma affecting the greater cornu of the hyoid bone. Only a handful of reports of primary chondrosarcoma involving the hyoid exist in the world literature. The case described presented as a swelling in the submandibular triangle, and as such posed a particular clinical and radiologic diagnostic challenge. Our subsequent surgical management of this rare entity comprised local excision followed by close observation, and is defined in the context of the existing literature. Two years after surgery, the patient remained free of tumor recurrence; she was subsequently lost to follow-up.

Leiomyosarcoma of the larynx: Case report and review of the literature

April 30, 2008     Jayant Sastri Goda, MD, DNB, Karuppiah Saravanan, MS, DNB, R.K. Vashistha, MD, FRCPath, Vinay Kumar, MD, and Ashok K. Gupta, MS
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Abstract

Leiomyosarcoma of the larynx is an extremely rare entity. This tumor is aggressive and is associated with dismal treatment results. We present a case of leiomyosarcoma of the larynx treated with surgery and postoperative radiotherapy. In this article we also discuss laryngeal leiomyosarcoma's clinical manifestations, associated diagnostic dilemmas, and optimal management, as well as a review of the literature.

Chondrosarcoma of the arytenoid cartilage: A case report and review of the literature

December 1, 2007     Stella Lee, MD, Anthony Sparano, MD, Paul Zhang, MD, and Natasha Mirza, MD
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Abstract

We report the case of a 56-year-old black woman with a locally aggressive chondrosarcoma at an unusual tumor site: the right arytenoid cartilage. The tumor extended from the superior pole of the right arytenoid cartilage to the soft-tissue areas of the right aryepiglottic fold, piriform sinus, and interarytenoid area. We undertook a conservative surgical approach by performing an endoscopic transoral CO2 laser resection, a right arytenoidectomy with wide soft-tissue margins, and a tracheotomy in anticipation of postoperative edema. Surgical exploration revealed that the tumor extended into the cricoid cartilage. Histopathology demonstrated a low-grade chondrosarcoma of the conventional variant. Clear margins were obtained by staged procedures. Chondrosarcomas of the larynx typically exhibit low-grade histopathology, and affected patients have a low incidence of metastasis and a good prognosis. Even so, these tumors can present diagnostic and therapeutic challenges. Surgical resection provides adequate airway protection and sound oncologic safety while preserving speech and swallowing, and these should be the surgeon's goals in this setting. Options include open laryngofissure, thyrotomy, organ preservation with partial laryngectomy, and endoscopic laser resection.

Radiation-induced osteosarcoma of the maxillary sinus

May 31, 2007     Sofia Avitia, MD; Ryan F. Osborne, MD, FACS

Embryonal rhabdomyosarcoma of the temporal bone

March 31, 2007     Borlingegowda Viswanatha, MS, DLO
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Follicular dendritic cell sarcoma of the tonsil: A case report and literature review

March 31, 2007     Chad McDuffie, MD; Timothy S. Lian, MD; Joel Thibodeaux, MD
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Ewing sarcoma and primitive neuroectodermal tumor

February 1, 2007     Lester D.R. Thompson, MD, FASCP

Supracricoid partial laryngectomy as a primary treatment for carcinosarcoma of the larynx

April 30, 2006     Kuauhyama Luna-Ortiz, MD; Adalberto Mosqueda-Taylor, DDS, MSc
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Abstract
Carcinosarcoma of the larynx is uncommon. When it does occur, its clinical features resemble those of sarcomatoid carcinoma, and its biologic behavior is similar to that of malignant mesenchymal neoplasms. We describe 2 cases of carcinosarcoma of the glottis. The tumors were staged as T3N0M0 and T2N0M0. Both patients were treated with supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Eight months postoperatively, 1 of the 2 patients experienced a recurrence of the sarcomatous component of the tumor, and he underwent a total laryngectomy. The other patient remained free of disease at 12 months of follow-up. We conclude that supracricoid partial laryngectomy may be offered as an organ-preserving measure even in patients with sarcomatous disease; total laryngectomy can be held in reserve as a rescue measure. Patients must be closely monitored for early detection of recurrence. The role of adjuvant therapy for sarcomatous neoplasms in this area has not yet been clearly established.

Vocal fold atrophy after resection of a parapharyngeal space sarcoma

April 1, 2006     Libby J. Smith, DO; Mary Hawkshaw, RN, BSN; Robert T. Sataloff, MD, DMA

Lower-extremity liposarcoma metastatic to the larynx: Case report

March 1, 2006     Scott F. Daly, MD; James Sciubba, DMD, PhD; Ralph P. Tufano, MD
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Abstract
Distant metastases to the larynx are rare. We describe the case of a 46-year-old man who was referred to our head and neck surgery clinic with a 6-week history of sore throat and otalgia. He was found to have a laryngeal lesion that was consistent with a primary myxoid liposarcoma that had been extirpated from a lower extremity earlier. To the best of our knowledge, no case of myxoid liposarcoma metastatic to the larynx has been previously reported in the English-language literature.
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