September 30, 2009 Amy Mettman, MD, Larry L. Myers, MD, and Kelley Carrick, MD
January 1, 2009 Akram Rahal, MD, FRCSC, Joseph R. Durio, PA-C, and Michael L. Hinni, MD
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Abstract
Chondrosarcoma of the nasal septum is a rarely encountered malignancy. When it does occur, early diagnosis is difficult because patients generally present with common, nonspecific sinonasal complaints. We describe a case of chondrosarcoma of the nasal septum in a 38-year-old Hispanic man. The lesion was discovered on computed tomography during a workup for symptoms of chronic sinus disease. The tumor was removed in its entirety and identified as a low-grade lesion that required no further treatment. The patient remained disease-free 4 years postoperatively. We review the diagnosis of this neoplasm and its treatment and follow-up.
September 25, 2008 Sanjay Verma, MBBCh, MA, FRCS (ORL-HNS), PhD, Perumal Chokkalingam, BSc, FRCS, and Duncan McRae, FRCS, FRCS (ORL-HNS)
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Abstract
We report an unusual case of a young woman with chondrosarcoma affecting the greater cornu of the hyoid bone. Only a handful of reports of primary chondrosarcoma involving the hyoid exist in the world literature. The case described presented as a swelling in the submandibular triangle, and as such posed a particular clinical and radiologic diagnostic challenge. Our subsequent surgical management of this rare entity comprised local excision followed by close observation, and is defined in the context of the existing literature. Two years after surgery, the patient remained free of tumor recurrence; she was subsequently lost to follow-up.
April 30, 2008 Jayant Sastri Goda, MD, DNB, Karuppiah Saravanan, MS, DNB, R.K. Vashistha, MD, FRCPath, Vinay Kumar, MD, and Ashok K. Gupta, MS
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Abstract
Leiomyosarcoma of the larynx is an extremely rare entity. This tumor is aggressive and is associated with dismal treatment results. We present a case of leiomyosarcoma of the larynx treated with surgery and postoperative radiotherapy. In this article we also discuss laryngeal leiomyosarcoma's clinical manifestations, associated diagnostic dilemmas, and optimal management, as well as a review of the literature.
December 1, 2007 Stella Lee, MD, Anthony Sparano, MD, Paul Zhang, MD, and Natasha Mirza, MD
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Abstract
We report the case of a 56-year-old black woman with a locally aggressive chondrosarcoma at an unusual tumor site: the right arytenoid cartilage. The tumor extended from the superior pole of the right arytenoid cartilage to the soft-tissue areas of the right aryepiglottic fold, piriform sinus, and interarytenoid area. We undertook a conservative surgical approach by performing an endoscopic transoral CO2 laser resection, a right arytenoidectomy with wide soft-tissue margins, and a tracheotomy in anticipation of postoperative edema. Surgical exploration revealed that the tumor extended into the cricoid cartilage. Histopathology demonstrated a low-grade chondrosarcoma of the conventional variant. Clear margins were obtained by staged procedures. Chondrosarcomas of the larynx typically exhibit low-grade histopathology, and affected patients have a low incidence of metastasis and a good prognosis. Even so, these tumors can present diagnostic and therapeutic challenges. Surgical resection provides adequate airway protection and sound oncologic safety while preserving speech and swallowing, and these should be the surgeon's goals in this setting. Options include open laryngofissure, thyrotomy, organ preservation with partial laryngectomy, and endoscopic laser resection.
May 31, 2007 Sofia Avitia, MD; Ryan F. Osborne, MD, FACS
March 31, 2007 Borlingegowda Viswanatha, MS, DLO
March 31, 2007 Chad McDuffie, MD; Timothy S. Lian, MD; Joel Thibodeaux, MD
February 1, 2007 Lester D.R. Thompson, MD, FASCP
April 30, 2006 Kuauhyama Luna-Ortiz, MD; Adalberto Mosqueda-Taylor, DDS, MSc
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Abstract
Carcinosarcoma of the larynx is uncommon. When it does occur, its clinical features resemble those of sarcomatoid carcinoma, and its biologic behavior is similar to that of malignant mesenchymal neoplasms. We describe 2 cases of carcinosarcoma of the glottis. The tumors were staged as T3N0M0 and T2N0M0. Both patients were treated with supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Eight months postoperatively, 1 of the 2 patients experienced a recurrence of the sarcomatous component of the tumor, and he underwent a total laryngectomy. The other patient remained free of disease at 12 months of follow-up. We conclude that supracricoid partial laryngectomy may be offered as an organ-preserving measure even in patients with sarcomatous disease; total laryngectomy can be held in reserve as a rescue measure. Patients must be closely monitored for early detection of recurrence. The role of adjuvant therapy for sarcomatous neoplasms in this area has not yet been clearly established.
April 1, 2006 Libby J. Smith, DO; Mary Hawkshaw, RN, BSN; Robert T. Sataloff, MD, DMA
March 1, 2006 Scott F. Daly, MD; James Sciubba, DMD, PhD; Ralph P. Tufano, MD
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Abstract
Distant metastases to the larynx are rare. We describe the case of a 46-year-old man who was referred to our head and neck surgery clinic with a 6-week history of sore throat and otalgia. He was found to have a laryngeal lesion that was consistent with a primary myxoid liposarcoma that had been extirpated from a lower extremity earlier. To the best of our knowledge, no case of myxoid liposarcoma metastatic to the larynx has been previously reported in the English-language literature.
