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Myeloid sarcomas of the head and neck in pediatric patients with myeloid leukemia

September 19, 2016  |  David W. Cuthbertson, MD; Jyotinder Nain Punia, MD; Vicki L. Owczarzak, MD


Myeloid sarcoma is a rare extramedullary tumor composed of malignant myeloid cells that occur in the presence of myeloid leukemia. We report a case series of pediatric head and neck myeloid sarcomas representative of the epidemiology, symptomatology, laboratorial correlations,...

Malignant transformation of a high-grade osteoblastoma of the petrous apex with subcutaneous metastasis

June 14, 2016  |  Casey T. Kraft, BS; Robert J. Morrison, MD; H. Alexander Arts, MD, FACS


We describe the clinical presentation, management, and pathologic findings in a case of osteosarcoma of the petrous apex with an atypical metastasis to the lower abdominal wall. We retrospectively reviewed the record of a 49-year-old man who was diagnosed with a right petrous...

Myxoinflammatory fibroblastic sarcoma of the nose: First reported case at an unusual location (nasal dorsum), with a review of the literature

March 16, 2016  |  Jura Numminen, PhD; Argyro Bizaki, MD; Jarno Kujansivu, MD; Sanna Huovinen, MD; Markus Rautiainen, MD, PhD


Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare, low-grade, malignant, soft-tissue tumor that typically affects the distal extremities of middle-aged patients. In most cases, it presents as a painless, slowly growing mass within the subcutaneous tissue. It is associated...

Pleomorphic sarcoma of the neck

September 21, 2015  |  Lester D. Thompson, MD

Pleomorphic sarcoma is an uncommon neoplasm in the head and neck now that refinements in diagnostic techniques have more accurately classified tumors that used to be placed in this category.

A large laryngeal pleomorphic leiomyosarcoma arising from a small pedicle without mucosal invasion: Case report

September 21, 2015  |  Napadon Tangjaturonrasme, MD


Laryngeal leiomyosarcoma is a rare mesenchymal malignancy of the head and neck region. The author presents a case of an atypical laryngeal leiomyosarcoma that featured a large pedunculated lesion without mucosal invasion. This feature has not been previously described in the...

A rare case of malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma NOS) of the vocal fold

July 21, 2015  |  Jin Pyeong Kim, MD; Jin Yong Kim, MD; Gyung Hyuck Ko, MD; Seung Hoon Woo, MD


Malignant fibrous histiocytoma, also known as pleomorphic undifferentiated sarcoma not otherwise specified, arises in numerous organs. The first-line treatment is complete excision of the mass, but in some cases postoperative chemo- and/or radiotherapy is recommended. Only a...

Biphasic synovial sarcoma of the hypopharynx

April 28, 2015  |  Ustun Osma, MD; Hülya Eyigor, MD; Dinc Suren, MD; Cem Sezer, MD; Mustafa Deniz Yilmaz, MD


Synovial sarcoma is a malignant mesenchymal neoplasm usually involving the extremities of young adults. Localization in the head and neck region is rare. Histologically, these lesions have biphasic and monophasic variants, the latter being more rare and difficult to identify....

Temporal bone chondrosarcoma: Presentation of 4 cases and review of the literature

December 19, 2014  |  Duoduo Tao, MD; Matthew R. Hoffman, MD; Bing Chen, MD, PhD

We describe 4 cases of chondrosarcoma of the temporal bone, which occurred in a 66-year-old man and in 3 women aged 34, 37, and 47 years. One of these patients was originally diagnosed with an epithelial cyst and another with a middle ear neoplasm. Three patients underwent surgical removal of...

Mesenchymal chondrosarcoma of the mandible: A rare malignant tumor

September 18, 2014  |  Rakesh Kumar Singh, MS; Saurabh Varshney, MS; Sampan Singh Bist, MS; Meena Harsh, MD; Nitin Gupta, MD


Mesenchymal chondrosarcoma (MCHS) is a highly aggressive, malignant, cartilaginous tumor that represents about 1% of all chondrosarcomas. Only about 50 cases of MCHS of the jaw have been reported in the English-language literature; maxillary tumors are much more common than...

Leiomyosarcoma of the parapharyngeal space: A very rare entity

July 14, 2014  |  Haim Gavriel, MD; Eyal Yeheskeli, MD; Gratiana Hermann, MD; Ephraim Eviatar, MD


Leiomyosarcoma of the head and neck is very rare, as only about 100 cases have been reported; of these, only 3 cases have been previously reported in the parapharyngeal space. We report the fourth such case, and we review the features of this entity. The patient was an 84-year-...

Pediatric rhabdomyosarcoma

July 14, 2014  |  Rosemary Ojo, MD; Si Chen, MD; Liset Pelaez, MD; Ramzi Younis, MD

All children with rhabdomyosarcoma require multimodality therapy to maximize local tumor control. This can involve different combinations of chemotherapy, surgery, and radiation therapy.

Rhabdomyosarcoma of the supraglottis in an adult

June 9, 2014  |  Alex Fernandez, MS; Reena Gupta, MD; Hootan Zandifar, MD

Primary laryngeal rhabdomyosarcoma is an extremely uncommon malignant neoplasm in adults, accounting for relatively few documented cases compared with squamous cell carcinoma.


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