Primary malignant melanoma of the epiglottis: A rare presentation

April 1, 2006     Rajaraman Durai, MS, MRCS; Syed Hashmi, FRCS
Primary malignant melanoma of the epiglottis is extremely rare. Until now, only 4 cases have been reported in the world literature. We describe a new case of epiglottic primary malignant melanoma in a 74-year-old man who presented with hoarseness and a foreign-body sensation. Clinical examination revealed the presence of a small, whitish, polypoid tumor on the laryngeal surface of the epiglottis; no other primary melanoma was detected. Wide excision of the lesion was performed, and microscopy revealed that it contained melanin-pigmented tumor cells in both the mucosa and submucosa. Immunostaining was positive for S-100 protein. The patient was treated with radiotherapy, and he remained well 1 year after the diagnosis with no evidence of recurrence.

The Karapandzic flap in recurrent melanoma of the lip

September 30, 2004     Lorraine M. Smith, MD, MPH; Ryan F. Osborne, MD
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