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Infection

Painful rash of the auricle: Herpes zoster oticus

December 19, 2014  |  Chao-Yin Kuo, MD; Yuan-Yung Lin, MD; Chih-Hung Wang, MD, PhD

A PCR assay in addition to conventional serologic testing provides quick confirmation of the diagnosis of herpes zoster oticus infection.

Efficacy of Intralipid infusion in reducing amphotericin-B-associated nephrotoxicity in head and neck invasive fungal infection: A randomized, controlled trial

February 20, 2017  |  Mehrdad Hasibi, MD; Sirous Jafari, MD; Seyyed Ali Dehghan Manshadi, MD; Marjan Asadollahi, MD; Mohammadreza Salehi, MD; Varasteh Vakili Zarch, MD; Ali Kouhi, MD

Abstract

Amphotericin B deoxycholate (ABD) is the best therapeutic agent available for the treatment of most systemic fungal infections. However, some untoward adverse effects such as nephrotoxicity may limit its appropriate therapeutic use. We conducted a randomized, controlled trial...

Invasive fungal laryngopharyngitis resulting in laryngeal destruction with complete laryngotracheal separation: Report of a case

January 25, 2017  |  Tyler Swiss, BS; Sergio Santino Cervantes, MD; Michael Hinni, MD; David G. Lott, MD

Abstract

As the treatment of hematopoietic cancers evolves, otolaryngologists will see a higher incidence of opportunistic infections. We discuss a case of invasive fungal disease that invaded the larynx, pharynx, trachea, and pulmonary parenchyma after chemotherapy. The patient, a 46-...

Acute bacterial meningitis caused by acute otitis media in adults: A series of 12 patients

January 25, 2017  |  Daniel M. Kaplan, MD; Ofer Gluck, MD; Mordechai Kraus, MD; Youval Slovik, MD; Hindy Juwad, Bsc

Abstract

We conducted a retrospective chart review to characterize the outcomes of 12 patients-9 men and 3 women, aged 21 to 79 years (mean: 49)-who had been treated at our tertiary care center for acute bacterial meningitis caused by acute otitis media (ABMAO). Fever was the most...

Blastomycosis of the nose: A case report

August 21, 2016  |  Thomas M. Jetmore, MD; Jennifer Phan, MD; Abideen O. Yekinni, MD, FACS

Abstract

Blastomyces dermatitidis is a thermally dimorphic fungus endemic to the North American soil near the Mississippi, Ohio, and St. Lawrence river valleys, as well as the Great Lakes Basin. It is responsible for blastomycosis, a systemic pyogranulomatous disease. Blastomycosis of...

Idiopathic nasal bone osteitis: A preliminary report on a recently recognized entity

August 21, 2016  |  Yotam Shkedy, MD; Ohad Ronen, MD; Sarah Gips, MD; Avi Front†; Tal Marshak, MD; Nechama Uri, MD

Abstract

Osteitis of the nasal bones is a rare disease; when it occurs, it usually has a known etiology. To the best of our knowledge, idiopathic nasal bone osteitis (NBO) has not been described before. We conducted a study to analyze the behavior of idiopathic NBO and its outcome and...

Detection of CMV DNA in the perilymph of a 6-year-old boy with congenital cytomegalovirus infection

June 14, 2016  |  Ina Foulon, MD; Oriane Soetens, PhD; Leen Vleurinck, MA; Frans Gordts, PhD; Astrid Leus, MD; Anne Naessens, PhD

Abstract

We present the case of a 6-year-old boy who received a cochlear implant for profound sensorineural hearing loss after being born with cytomegalovirus (CMV) infection. Even after 6 years, CMV DNA was still found in the perilymph of the cochlea. Our case shows that CMV DNA can be...

Rhinosporidiosis

March 16, 2016  |  Lester D. Thompson, MD

Surgical treatment is the mainstay of therapy for rhinosporidiosis, but there is a 10% recurrence rate.

Helicobacter pylori in lacrimal secretions

March 16, 2016  |  Aysegul Batioglu-Karaaltin, MD; Ozlem Saatci, MD; Meltem Akpinar, MD; Melih Ozgur Celik, PhD; Omer Develioglu, MD; Ozgur Yigit, MD; Mehmet Kulekci, MD; Alper Tunga Akarsubasi, PhD

Abstract

The aim of this study was to investigate the presence of Helicobacter pylori in human lacrimal and nasal secretions. Eighty patients with complaints of dyspepsia who had undergone endoscopies and gastric antrum biopsies were included in the study. A total of five...

Granulomatous ulcers of the nose and oropharynx: Lupus vulgaris revisited

February 24, 2016  |  Mainak Dutta, MS; Soumya Ghatak, MS; Ramanuj Sinha, MS, DNB

Lupus vulgaris manifests as a postprimary chronic granulomatous ulcer in patients with moderate to good immunity.

Laryngotracheal mucormycosis: Report of a case

January 22, 2016  |  Jillian Mattioni, DO; Joel E. Portnoy, MD; Jaime Eaglin Moore, MD; David Carlson, DO; Robert T. Sataloff, MD, DMA, FACS

Abstract

Airway mucormycosis is a deadly opportunistic infection that affects immunocompromised persons, particularly diabetics and those undergoing chemotherapy. Although it is typically a pulmonary or sinonasal infection, mucormycosis can affect the larynx and trachea, with...

Nasal myiasis: A case report

July 21, 2015  |  Zrria L. White, MD; Michael W. Chu, MD; Richard J. Hood, MD

Abstract

Nasal myiasis is a rare condition, with only a few reported cases and no treatment consensus. We propose a conservative treatment approach with saline irrigation and debridement. Two patients in the ICU of Norfolk General Hospital, a tertiary academic referral center, presented...

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