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Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: A meta-analysis

February 24, 2016  |  Nopawan Vorasubin, MD; Chau Nguyen, MD, FACS; Marilene Wang, MD


A number of studies of predictive factors for lymph node metastasis in papillary thyroid microcarcinoma have been published. We conducted a systematic meta-analysis of some of these studies, and we present our findings herein. We searched the PubMed database and found 13...

Concurrent chemoradiotherapy with capecitabine/cisplatin versus 5-fluorouracil/cisplatin in resectable laryngohypopharyngeal squamous cell carcinoma

February 24, 2016  |  Dongbin Ahn, MD; Jin Ho Sohn, MD, PhD; Jae Hyug Kim, MD; Jeong Eun Lee, MD; Shin Hyung Park, MD; Jae Chul Kim, MD


A combination of 5-fluorouracil and cisplatin (FP regimen) is widely used as a standard treatment for head and neck cancer. Recently, capecitabine has received increased attention. We conducted a retrospective study to compare the efficacy and safety of the FP regimen with that...

Intratonsillar metastasis of EBV-positive nasopharyngeal carcinoma

January 22, 2016  |  Matthew R. Naunheim, MD, MBA; Linda N. Lee, MD; Harrison W. Lin, MD; Peter M. Sadow, MD, PhD; Daniel G. Deschler, MD


We present the case of a 47-year-old man with a history of Epstein-Barr-virus-positive nasopharyngeal carcinoma who developed a metastasis to the palatine tonsil. To the best of our knowledge, this is the first reported case of an intratonsillar metastasis of a nasopharyngeal...

Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature

January 22, 2016  |  Valerie Zielinski, MD; Simon Laban, MD; Silke Tribius, MD; Phillipe Schafhausen, MD; Simon Veldhoen, MD; Rainald Knecht, PhD; Till Clauditz, MD; Adrian Muenscher, MD


Sinonasal undifferentiated carcinoma (SNUC) represents less than 1% of all malignancies. Most of the tumors are diagnosed at an advanced stage, when they have already invaded neighboring tissue structures. We describe the cases of 2 patients with a substantial intracerebral...

Reconstruction after resection of a lower lip squamous cell carcinoma with a submental island flap

December 14, 2015  |  Jin Pyeong Kim, MD; Hyun Woo Park, MD; Jung Je Park, MD; Seung Hoon Woo, MD


Lip cancer is the most common malignancy of the oral cavity and the second most common cancer in the head and neck. Typically, squamous cell carcinoma of the lower lip is an ulcerated lesion with raised margins. Surgery is the best treatment for lower lip cancer. The lips are...

"Cannonball" delayed pulmonary metastases in parotid adenoid cystic carcinoma

October 31, 2015  |  David X. Liu, BS; Juan S. Gomez, MD; Enrique Palacios, MD, FACR; Jeremy Nguyen, MD

Optimal imaging studies for perineural invasion can be obtained with magnetic resonance imaging, which demonstrates abnormal enhancement of the cranial nerves involved.

Masseter flap for reconstruction of defects after excision of buccal mucosa cancers with intact mandible

October 31, 2015  |  Pankaj Chaturvedi, MS; Sandeep Lerra, MS(ENT); Farheen Ustad, MS; Prathamesh S. Pai, MS(ENT); Devendra A. Chaukar, MS; Anil K. D'Cruz, MS


Among the reconstructive options available for buccal mucosa defects with an intact mandible, free flap with microvascular anastomosis is the best option. However, in the developing world, with poor resources, limited infrastructure, and high patient load, this cannot be...

Silastic injection for vocal fold medialization resulting in a false-positive finding on F18 FDG-PET/CT

September 21, 2015  |  Ayman Mahfouz, MBBS; Meeran Naji, MSc, MRCS, FRCR; Wing Yan Mok, BSc, MBBS, FRCR; Ali S. Taghi, MBBS, MD, FRCS(ORL-HNS); Zarni Win, MRCP, FRCR


A false-positive uptake of F18-fluorodeoxyglucose (FDG) on positron-emission tomography/computed tomography (PET/CT) can result in confusion and misinterpretation of scans. Such uptakes have been previously described after injection of polytetrafluoroethylene (Teflon) into the...

Salivary gland adenoid cystic carcinoma

July 21, 2015  |  Lester D.R. Thompson, MD

Tumors are poorly circumscribed with an infiltrative border, including extracapsular extension beyond the salivary gland.

Oncocytic mucoepidermoid carcinoma of the parotid gland: A case report and review of the literature

July 21, 2015  |  Deepali Jain, MD; Nabeen C. Nayak, MD


Oncocytic metaplasia rarely has been reported in mucoepidermoid carcinomas. Most salivary gland lesions with oncocytic change are benign; therefore, it is important to distinguish mucoepidermoid carcinoma from other entities that may show prominent oncocytic change. We report a...

Chronic discharging ear and multiple cranial nerve pareses: A sinister liaison

April 28, 2015  |  Mainak Dutta, MS; Dipankar Mukherjee, MS; Subrata Mukhopadhyay, MS

SCC of the temporal bone might well represent the extreme of the “inflammation-metaplasia-dysplasia-carcinoma” sequence, with chronic otitis media representing the inflammation.

Sinonasal undifferentiated carcinoma as a third primary neoplasm: A case report and review of the literature

April 28, 2015  |  John J. Chi, MD; Michael D. Feldman, MD; James N. Palmer, MD


A 71-year-old man with a history of a pituitary prolactinoma and metastatic pancreatic carcinoma presented with epistaxis, visual changes, bilateral ophthalmoplegia, involuntary closure of the left eye, and ptosis of the right eye. The patient was found to have a soft-tissue...


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