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Carcinoma

Synchronous bilateral tonsillar squamous cell carcinoma related to human papillomavirus: Two case reports and a brief review of the literature

April 30, 2016  |  Allison Rasband-Lindquist, MD; Yelizaveta Shnayder, MD; Maura O'Neil, MD

Abstract

Human papillomavirus (HPV) was recently identified as a risk factor for oropharyngeal squamous cell carcinoma (SCC) independent of tobacco and alcohol use. The prognosis of patients with HPV-related oropharyngeal carcinomas is better than that for patients with non-HPV-related...

Is unenhanced 18F-FDG-PET/CT better than enhanced CT in the detection of retropharyngeal lymph node metastasis in nasopharyngeal carcinoma?

April 30, 2016  |  Iuan-Sheng Wu, MD; Guang-Uei Hung, MD; Bo-Ling Chang, MD; Chi-Kuang Liu, MD; Tung-Hao Chang, MD; Hong-Shen Lee, PhD; Mu-Kuan Chen, MD, MS, PhD

Abstract

Positron-emission tomography/computed tomography (PET/CT) has been proposed as a means to enhance the pretreatment evaluation of cervical lymph node status in patients with nasopharyngeal carcinoma (NPC). We conducted a prospective study to compare PET/CT and enhanced CT for...

A case of minocycline-induced black thyroid associated with papillary carcinoma

March 16, 2016  |  Kohei Nishimoto, MD, PhD; Yoshihiko Kumai, MD, PhD; Daizo Murakami, MD, PhD; Eiji Yumoto, MD, PhD

Abstract

We report a rare case of black thyroid accompanied by papillary carcinoma in a patient with an extended history of minocycline treatment. A 78-year-old man was referred to our outpatient clinic with swelling in his neck. He had been taking minocycline for the previous 2 years...

Metastatic pilomatrix carcinoma: Not so rare after all? A case report and review of the literature

March 16, 2016  |  Daniel M. Walker, MBBS; Samuel Dowthwaite, MBBS, FRACS; Drew Cronin, MBBS; Tristan Molden-Hauer, MBBS; Brent McMonagle, MBBS, FRACS

Abstract

Pilomatrixoma is a slowly growing benign tumor of the dermal hair cells. Metastatic disease is exceptionally rare. Pilomatrixoma can occur at any age, but most patients are older than 40 years at presentation. Approximately 60% of these lesions occur in the head and neck region...

Papillary carcinoma in thyroglossal duct cyst: Two case reports and review of the literature

March 16, 2016  |  Neil S. Patel, MD; Kianoush Sheykholeslami, MD, PhD

Abstract

The thyroglossal duct cyst is one of the more common congenital anterior neck masses. In rare cases, carcinoma has been detected within one of these cysts on histopathologic analysis of resected tissue. Since the incidence of thyroglossal duct cyst carcinoma is low, the...

Concurrent chemoradiotherapy with capecitabine/cisplatin versus 5-fluorouracil/cisplatin in resectable laryngohypopharyngeal squamous cell carcinoma

February 24, 2016  |  Dongbin Ahn, MD; Jin Ho Sohn, MD, PhD; Jae Hyug Kim, MD; Jeong Eun Lee, MD; Shin Hyung Park, MD; Jae Chul Kim, MD

Abstract

A combination of 5-fluorouracil and cisplatin (FP regimen) is widely used as a standard treatment for head and neck cancer. Recently, capecitabine has received increased attention. We conducted a retrospective study to compare the efficacy and safety of the FP regimen with that...

Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: A meta-analysis

February 24, 2016  |  Nopawan Vorasubin, MD; Chau Nguyen, MD, FACS; Marilene Wang, MD

Abstract

A number of studies of predictive factors for lymph node metastasis in papillary thyroid microcarcinoma have been published. We conducted a systematic meta-analysis of some of these studies, and we present our findings herein. We searched the PubMed database and found 13...

Intratonsillar metastasis of EBV-positive nasopharyngeal carcinoma

January 22, 2016  |  Matthew R. Naunheim, MD, MBA; Linda N. Lee, MD; Harrison W. Lin, MD; Peter M. Sadow, MD, PhD; Daniel G. Deschler, MD

Abstract

We present the case of a 47-year-old man with a history of Epstein-Barr-virus-positive nasopharyngeal carcinoma who developed a metastasis to the palatine tonsil. To the best of our knowledge, this is the first reported case of an intratonsillar metastasis of a nasopharyngeal...

Management of sinonasal undifferentiated carcinoma with intracerebral invasion: Clinical experience at a single institution and review of the literature

January 22, 2016  |  Valerie Zielinski, MD; Simon Laban, MD; Silke Tribius, MD; Phillipe Schafhausen, MD; Simon Veldhoen, MD; Rainald Knecht, PhD; Till Clauditz, MD; Adrian Muenscher, MD

Abstract

Sinonasal undifferentiated carcinoma (SNUC) represents less than 1% of all malignancies. Most of the tumors are diagnosed at an advanced stage, when they have already invaded neighboring tissue structures. We describe the cases of 2 patients with a substantial intracerebral...

Reconstruction after resection of a lower lip squamous cell carcinoma with a submental island flap

December 14, 2015  |  Jin Pyeong Kim, MD; Hyun Woo Park, MD; Jung Je Park, MD; Seung Hoon Woo, MD

Abstract

Lip cancer is the most common malignancy of the oral cavity and the second most common cancer in the head and neck. Typically, squamous cell carcinoma of the lower lip is an ulcerated lesion with raised margins. Surgery is the best treatment for lower lip cancer. The lips are...

"Cannonball" delayed pulmonary metastases in parotid adenoid cystic carcinoma

October 31, 2015  |  David X. Liu, BS; Juan S. Gomez, MD; Enrique Palacios, MD, FACR; Jeremy Nguyen, MD

Optimal imaging studies for perineural invasion can be obtained with magnetic resonance imaging, which demonstrates abnormal enhancement of the cranial nerves involved.

Masseter flap for reconstruction of defects after excision of buccal mucosa cancers with intact mandible

October 31, 2015  |  Pankaj Chaturvedi, MS; Sandeep Lerra, MS(ENT); Farheen Ustad, MS; Prathamesh S. Pai, MS(ENT); Devendra A. Chaukar, MS; Anil K. D'Cruz, MS

Abstract

Among the reconstructive options available for buccal mucosa defects with an intact mandible, free flap with microvascular anastomosis is the best option. However, in the developing world, with poor resources, limited infrastructure, and high patient load, this cannot be...

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