Adenocarcinoma

Recurrent polymorphous low-grade adenocarcinoma manifesting as a sinonasal mass: A case report

May 31, 2005     Daniel D. Charous, MD; Mary F. Cunnane, MD; Marc R. Rosen, MD; William M. Keane, MD
article
Abstract
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm that tends to follow a benign clinical course. Recurrences are uncommon. We report a case of recurrent PLGA of the paranasal sinuses that manifested as a large mass that filled the entire nasal cavity and left maxillary sinus. To our knowledge, this is the first reported case of a recurrent PLGA of the paranasal sinuses.

Metastasis of colonic adenocarcinoma to the external ear canal: An unusual case with a complex pattern of disease progression

January 1, 2005     Henry J. Carson, MD; Jeffrey S. Krivit, MD; Stanley G. Eilers, MD
article
Abstract
We report on a patient who developed far-ranging metas-tases of adenocarcinoma of the colon that followed a gradual cephalad progression, including the right external ear canal, and led to hearing loss. The patient was a 63-year-old white male with stage III adenocarcinoma of the colon. After 2 years with metastases elsewhere, he developed hearing loss on the right side. Physical examination of the head and neck showed a mass in the external ear canal, and biopsy confirmed adenocarcinoma. After removal, the patient's hearing improved. This case is interesting not only because of the unusual metastasis to the external ear canal, but also because of the patient's previous history of metastasis over the course of more than 2 years. The significance of such wide-ranging metastases is that metastasis of adenocarcinoma to the ear did not signal imminent death, and relief of the hearing loss it caused was possible.
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