Adenocarcinoma

Ceruminous adenocarcinoma of the ear

May 7, 2014     Jagdeep Singh Virk, MA (Cantab), MRCS, DOHNS; Gaurav Kumar, FRCS(ORL-HNS); Sherif Khalil, MS, FRCS(ORL-HNS), MD
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Ceruminous carcinomas are extremely rare and tend to present as a mass or with otalgia. They are difficult to diagnose histopathologically (in part due to varied and nonstandardized nomenclature).

Polymorphous low-grade adenocarcinoma

January 21, 2014     Lester D.R. Thompson, MD
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PLGA affects the palate (60% of cases) most commonly, especially at the mucosal junction of the hard and soft palates; the next most common sites are the cheek and the lip, often the upper lip.

Primary adenocarcinoma of the frontal sinus

October 26, 2011     Raman Wadhera, MS, S.P. Gulati, MS, Ajay Garg, MS, Anju Ghai, MD, and Sanjay Kumar, MD
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Abstract

When tumor involvement of the frontal sinus occurs, it is usually the result of the direct spread of the mass from the nasal cavity or anterior ethmoid sinuses. Primary frontal sinus tumors are extremely rare. We describe a case of primary adenocarcinoma of the frontal sinus in a 53-year-old man. The patient refused surgery, so he was treated with chemotherapy followed by radiotherapy. At the 1-year follow-up, only a slight reduction of the swelling was noted. Thereafter, he was lost to follow-up. This case represents a typical example of a paranasal cancer extending beyond the bony margins, with a silent onset that simulated benign disease. The best hope for an early diagnosis of such a tumor lies in the greater use of computed tomography to assess chronic rhinosinusitis.

Clear cell adenocarcinoma of the base of the tongue: A case report and review of the literature

April 30, 2011     Augusto Pietro Casani, MD, Manuela Marchetti, MD, Veronica Seccia, MD, Gabriella Fontanini, MD, Maria Elena Filice, MD, and Luca Muscatello, MD
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Abstract

Clear cell adenocarcinoma is an extremely rare tumor of the head and neck region. We report a case of a 75-year-old Caucasian woman with a 10-day history of hemoptysis but with no pain or other significant symptoms. A head and neck computed tomography scan with contrast medium showed an irregular, soft-tissue-like, irregularly enhanced lesion of the base of the tongue extending to its posterolateral portion. The tumor reached the lateral wall of the oropharynx, which showed a nonhomogeneous aspect. The patient underwent resection of the tumor via a conservative transmandibular approach. A clear cell adenocarcinoma of the base of the tongue is rarely a primary malignant lesion; it is more frequently a secondary lesion from a metastatic renal tumor. Because of this neoplasm's relatively slow growth rate and low incidence of metastasis or local recurrence, the gold standard of treatment is complete excision of the tumor with a sufficient tumor-free margin.

Rectal adenocarcinoma metastatic to the larynx

March 31, 2011     Joseph Q. Ta, MD and John Y. Kim, MD
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Abstract

Malignancies metastatic to the larynx are rare, accounting for fewer than 1% of all laryngeal cancers with metastatic sources; the most common of these metastases are cutaneous melanomas and renal cell carcinomas. Only 13 cases of colon cancer and 2 cases of rectal adenocarcinoma metastatic to the larynx have been previously reported in the literature. We report a new case of rectal adenocarcinoma metastatic to the larynx that resulted in subglottic stenosis in a 60-year-old man. We also review the literature, and we discuss the presentations of and treatments for this rare entity.

Papillary cystadenocarcinoma originating from a minor salivary gland with lymph node metastases

March 1, 2011     Demet Etit, MD, Nese Ekinci, MD, Gozde Evcim, MD, and Kazim Onal, MD
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Abstract

Papillary cystadenocarcinoma is a rare malignant neoplasm of the salivary glands. This tumor most commonly arises in the major salivary glands, mainly in the parotid gland, and rarely metastasizes to regional lymph nodes. We report here a case of papillary cystadenocarcinoma originating from a minor salivary gland, localized in the lateral portion of the tongue and with neck metastases, in a 57-year old woman. We discuss histopathologic and clinical features of this lesion and review the literature.

Tonsillar metastasis of signet-ring cell adenocarcinoma of the colon

July 31, 2010     Kelly K. Park, MD and Youn W. Park, MD, FACS
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Abstract

Cases of primary colorectal signet-ring cell carcinoma metastatic to the tonsil are extremely rare. To the best of our knowledge, only 4 such cases have been previously reported in the literature. We report a new case in a 76-year-old white woman. She was treated with chemotherapy, but her disease continued to spread and she was eventually placed on comfort care and palliative radiation therapy. The manner in which tonsillar metastases evolve is still unknown, but some hypotheses have been proposed, and we briefly review these theories.

Intestinal-type sinonasal adenocarcinoma

January 1, 2010     Lester D.R. Thompson, MD
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Gastric carcinoma

March 31, 2007     Catherine J. Rees, MD; Peter C. Belafsky, MD, PhD
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Low-grade adenocarcinoma of the nasal cavity-an unusual presentation: Case report and review of the literature

February 1, 2007     Brian J. Baumgartner, MD; Tremaine Ladd, MD; Carlos Esquivel, MD
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Polymorphous low-grade adenocarcinoma of the parotid gland

September 30, 2006     Ashli K. O'Rourke, MD; Christine G. Gourin, MD; Zane K. Wade, MD; Richard B. Hessler, MD
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Abstract
Polymorphous low-grade adenocarcinoma (PLGA) of the parotid gland is rare. We describe a new case in which the patient underwent parotidectomy only to experience an extensive recurrence 2 years later. The recurrence was treated with radical surgical excision and radiation therapy, and the patient remained disease-free at 5 years of follow-up. We also review the literature on primary parotid PLGA.

Sinonasal intestinal-type adenocarcinoma

August 31, 2006     Enrique Palacios, MD, FACR; Rafael Rojas, MD
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