October 26, 2011 Raman Wadhera, MS, S.P. Gulati, MS, Ajay Garg, MS, Anju Ghai, MD, and Sanjay Kumar, MD
article
Abstract
When tumor involvement of the frontal sinus occurs, it is usually the result of the direct spread of the mass from the nasal cavity or anterior ethmoid sinuses. Primary frontal sinus tumors are extremely rare. We describe a case of primary adenocarcinoma of the frontal sinus in a 53-year-old man. The patient refused surgery, so he was treated with chemotherapy followed by radiotherapy. At the 1-year follow-up, only a slight reduction of the swelling was noted. Thereafter, he was lost to follow-up. This case represents a typical example of a paranasal cancer extending beyond the bony margins, with a silent onset that simulated benign disease. The best hope for an early diagnosis of such a tumor lies in the greater use of computed tomography to assess chronic rhinosinusitis.
April 30, 2011 Augusto Pietro Casani, MD, Manuela Marchetti, MD, Veronica Seccia, MD, Gabriella Fontanini, MD, Maria Elena Filice, MD, and Luca Muscatello, MD
article
Abstract
Clear cell adenocarcinoma is an extremely rare tumor of the head and neck region. We report a case of a 75-year-old Caucasian woman with a 10-day history of hemoptysis but with no pain or other significant symptoms. A head and neck computed tomography scan with contrast medium showed an irregular, soft-tissue-like, irregularly enhanced lesion of the base of the tongue extending to its posterolateral portion. The tumor reached the lateral wall of the oropharynx, which showed a nonhomogeneous aspect. The patient underwent resection of the tumor via a conservative transmandibular approach. A clear cell adenocarcinoma of the base of the tongue is rarely a primary malignant lesion; it is more frequently a secondary lesion from a metastatic renal tumor. Because of this neoplasm's relatively slow growth rate and low incidence of metastasis or local recurrence, the gold standard of treatment is complete excision of the tumor with a sufficient tumor-free margin.
March 31, 2011 Joseph Q. Ta, MD and John Y. Kim, MD
article
Abstract
Malignancies metastatic to the larynx are rare, accounting for fewer than 1% of all laryngeal cancers with metastatic sources; the most common of these metastases are cutaneous melanomas and renal cell carcinomas. Only 13 cases of colon cancer and 2 cases of rectal adenocarcinoma metastatic to the larynx have been previously reported in the literature. We report a new case of rectal adenocarcinoma metastatic to the larynx that resulted in subglottic stenosis in a 60-year-old man. We also review the literature, and we discuss the presentations of and treatments for this rare entity.
March 1, 2011 Demet Etit, MD, Nese Ekinci, MD, Gozde Evcim, MD, and Kazim Onal, MD
article
Abstract
Papillary cystadenocarcinoma is a rare malignant neoplasm of the salivary glands. This tumor most commonly arises in the major salivary glands, mainly in the parotid gland, and rarely metastasizes to regional lymph nodes. We report here a case of papillary cystadenocarcinoma originating from a minor salivary gland, localized in the lateral portion of the tongue and with neck metastases, in a 57-year old woman. We discuss histopathologic and clinical features of this lesion and review the literature.
July 31, 2010 Kelly K. Park, MD and Youn W. Park, MD, FACS
article
Abstract
Cases of primary colorectal signet-ring cell carcinoma metastatic to the tonsil are extremely rare. To the best of our knowledge, only 4 such cases have been previously reported in the literature. We report a new case in a 76-year-old white woman. She was treated with chemotherapy, but her disease continued to spread and she was eventually placed on comfort care and palliative radiation therapy. The manner in which tonsillar metastases evolve is still unknown, but some hypotheses have been proposed, and we briefly review these theories.
January 1, 2010 Lester D.R. Thompson, MD
March 31, 2007 Catherine J. Rees, MD; Peter C. Belafsky, MD, PhD
February 1, 2007 Brian J. Baumgartner, MD; Tremaine Ladd, MD; Carlos Esquivel, MD
September 30, 2006 Ashli K. O'Rourke, MD; Christine G. Gourin, MD; Zane K. Wade, MD; Richard B. Hessler, MD
article
Abstract
Polymorphous low-grade adenocarcinoma (PLGA) of the parotid gland is rare. We describe a new case in which the patient underwent parotidectomy only to experience an extensive recurrence 2 years later. The recurrence was treated with radical surgical excision and radiation therapy, and the patient remained disease-free at 5 years of follow-up. We also review the literature on primary parotid PLGA.
August 31, 2006 Enrique Palacios, MD, FACR; Rafael Rojas, MD
December 1, 2005 Alfio J. Tincani, MD, PhD; Albina Altemani, MD, PhD; Antonio S. Martins, MD, PhD; Gilson Barreto, MD; João B. Valério, MD; André Del Negro, MD; Priscila P.C. Araújo, MD
article
Abstract
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those in the palate. We report a case of PLGA that arose in the base of the tongue and subsequently metastasized to the neck. The tumor was resected through the oral cavity with wide margins and dissection. The neck metastasis was treated with radical neck dissection and radiotherapy. The patient recovered and remained disease-free at follow-up 30 months later. This case shows that PLGA, which has a variable morphologic appearance, can occur at sites other than the salivary glands.
May 31, 2005 Daniel D. Charous, MD; Mary F. Cunnane, MD; Marc R. Rosen, MD; William M. Keane, MD
article
Abstract
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm that tends to follow a benign clinical course. Recurrences are uncommon. We report a case of recurrent PLGA of the paranasal sinuses that manifested as a large mass that filled the entire nasal cavity and left maxillary sinus. To our knowledge, this is the first reported case of a recurrent PLGA of the paranasal sinuses.
