Tongue

Polymorphous low-grade adenocarcinoma at the base of the tongue: An unusual location

December 1, 2005     Alfio J. Tincani, MD, PhD; Albina Altemani, MD, PhD; Antonio S. Martins, MD, PhD; Gilson Barreto, MD; João B. Valério, MD; André Del Negro, MD; Priscila P.C. Araújo, MD
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Abstract
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those in the palate. We report a case of PLGA that arose in the base of the tongue and subsequently metastasized to the neck. The tumor was resected through the oral cavity with wide margins and dissection. The neck metastasis was treated with radical neck dissection and radiotherapy. The patient recovered and remained disease-free at follow-up 30 months later. This case shows that PLGA, which has a variable morphologic appearance, can occur at sites other than the salivary glands.

Macroglossia secondary to systemic amyloidosis: Case report and literature review

May 31, 2005     Sandra Doria Xavier, MD; Ivo Bussoloti Filho, PhD; Helena Müller, MD
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Abstract
Amyloidosis is characterized by an abnormal extracellular deposition of amyloid in different tissues and organs, where it usually causes some type of dysfunction. Its cause is unknown. The two main forms of amyloidosis are systemic and localized; the latter is rare. No satisfactory treatment for systemic amyloidosis has been discovered, and mean survival is poor, ranging from 5 to 15 months depending on the presence or absence of multiple myeloma. We report a case of primary systemic amyloidosis in a 71-year-old man. The diagnosis of amyloidosis was established by tongue biopsy, and its systemic nature was identified by analysis of aspirated abdominal fat. At the 1-year follow-up, the patient's clinical condition had not changed, and he was thereafter lost to follow-up.

A means of achieving more surgical exposure during transoral surgery on the tongue base and vallecula

April 30, 2005     Yi-Shing Leu, MD; Guan-Min Ho, MD, PhD
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Radiation-induced sarcoma of the base of the tongue

November 1, 2004     Jason Hamilton, MD; Sofia Avitia, MD; Ryan F. Osborne, MD; Jimmy J. Brown, MD
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Nevoid basal cell carcinoma syndrome and fetal rhabdomyoma: A case study

September 30, 2004     Joseph Watson, DO; Kalpana Depasquale, DO; Mahmoud Ghaderi, DO; Seth Zwillenberg, MD
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Abstract
Fetal rhabdomyoma is not generally considered part of nevoid basal cell carcinoma syndrome. However, a review of the literature revealed five patients with this syndrome who also had fetal rhabdomyomas in various locations. We report the first patient with nevoid basal cell carcinoma syndrome and a fetal rhabdomyoma of the tongue. We recommend that embryonal rhabdomyosarcoma be ruled out to avoid overly aggressive treatment of these patients.

Pleomorphic adenoma of the base of the tongue

August 31, 2004     Sandeep Berry, MRCS; Huey Tay, FRCS; Carlos P. Puentes, MRC(Path)
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Abstract
We describe a rare case of pleomorphic adenoma involving the base of the tongue and adjacent valleculae. We also discuss the incidence, diagnosis, and treatment of these cases.

Torus mandibularis: An unusual cause of obstructive sleep apnea

April 30, 2004     Alan J. Saffran, MD; Richard F. Clark, PA-C
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