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Skull Base

Enchondroma of the skull base secondary to generalized enchondromatosis: A case report and review of the literature

November 22, 2011  |  Derek J. Rogers, MD, Mark E. Boseley, MD, Mark J. Stephan, MD, Samuel Browd, MD, PhD, and David C. Semerad, MD


Generalized enchondromatosis, of which Ollier disease is the most common type, is a rare bone dysplasia characterized by multiple intraosseous tumors near growth-plate cartilage. These cartilaginous tumors have a propensity to transform into chondrosarcomas. Enchondromas of the...

Osteosarcoma of the skull base in a 15-year-old boy

October 27, 2011  |  Gretchen M. Oakley, BA, Dary J. Costa, MD, Ron B. Mitchell, MD, and Cirilo Sotelo, MD

Skull base osteomyelitis originating in the middle ear or mastoid: A review of 3 cases

March 1, 2011  |  Aaron Pang, MBBS, MRCS(Edin) and Kevin Chong, MBBS, FRCS(Edin)


Skull base osteomyelitis is a life-threatening condition that sometimes arises as a sequela of otitis media and mastoiditis. We present a retrospective analysis of the clinical course of 3 patients with skull base osteomyelitis that originated in the middle ear or mastoid. All...

Skull base presentation of multiple myeloma

January 1, 2011  |  Anil Joshi, MRCS, MS, Dan Jiang, FRCS, Pranay Singh, MRCS, and David Moffat, BSc, MA, FRCS


Pathologic proliferation of the plasma cell population can produce a wide spectrum of disorders, ranging from benign solitary plasmacytoma to malignant multiple myeloma. The presentation of the resulting disease can be either localized or systemic, depending on the affected...

Role of irrigation with hypertonic saline for a recurrent skull base hydatid cyst: Case report and review of the literature

September 1, 2010  |  Sadaf Zia, FCPS, Ather Enam, MD, Iftikhar Salahuddin, MD, and Aslam Khan, MD


Hydatid cyst is a parasitic disease caused by the tapeworm Echinococcus granulosus. This disease is a rare finding in the head and neck region, and its presentation varies according to the area involved. We report the case of a 25-year-old woman who presented with...

Radiologic findings after successful chemoradiation for nasopharyngeal cancer with skull base erosion

January 1, 2010  |  Federico Ampil, MD, Guillermo Sangster, MD, Glenn Mills, MD, Cherie Ann Nathan, MD, Timothy Lian, MD, and Andrew Hall, BS


Nonoperative management is generally accepted as a treatment strategy for nasopharyngeal cancer characterized by destruction of the skull base. Chemoradiotherapy is considered the standard of care in these cases. We report a case in which imaging studies documented the...

Correlation between otitis media and craniofacial morphology in adults

December 1, 2007  |  Renata C. Di Francesco, MD, PhD, Perboyre Lacerda Sampaio, MD, PhD, and Ricardo Ferreira Bento, MD, PhD


We conducted a comparison study to determine if the development of otitis media in adults is correlated with craniofacial morphology. Our study population was made up of 66 adults, aged 18 to 40 years; 32 of these patients had otitis media and 34 did not. All subjects underwent...

Recurrence of isolated multiple myeloma in the skull base: A case report and review of the literature

September 1, 2007  |  Omar F. Husein, MD; Abraham Jacob, MD; Douglas D. Massick, MD; D. Bradley Welling, MD, PhD
Extramedullary plasmacytoma involving the skull base is rare. We describe what we believe is the first reported...

Long-term follow-up of a multiloculated arachnoid cyst of the middle cranial fossa

June 1, 2007  |  Marc A. Cohen, MD; Noam A. Cohen, MD, PhD; Gul Moonis, MD; David W. Kennedy, MD
Arachnoid cysts are benign intracranial lesions that are typically diagnosed incidentally. We describe the case...

Skull base thrombotic mycosis

March 1, 2007  |  Eric P. Wilkinson, MD; Robert A. Robinson, MD, PhD; Douglas K. Trask, MD, PhD

Synovial chondromatosis of the temporomandibular joint space

June 1, 2005  |  Jason S. Hamilton, MD; Sean Jones-Quaidoo, MD; Ryan F. Osborne, MD

The carotid-vertebral space: An 'extended' lateral window to the ventromedial cranial base and lower craniocervical junction

May 1, 2005  |  Amin B. Kassam, MD; Atul Patel, MD; William Welch, MD; Jeffrey Balzer, PhD; Carl Snyderman, MD; Barry Hirsch, MD; Ricardo Carrau, MD
We describe a unique method of accessing the ventromedial skull base and lower craniocervical junction. Our...


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