Sialoblastoma: A rare submandibular gland neoplasm

June 30, 2006     D.J. Verret, MD; Rene L. Galindo, MD, PhD; Robert J. DeFatta, MD, PhD; Paul W. Bauer, MD
A sialoblastoma is a rare congenital epithelial tumor that arises in a major salivary gland. To our knowledge, only 24 cases of sialoblastoma have been previously reported in the English-language literature. We report a new case, that of a 15-month-old boy who presented with a submandibular mass. Surgical excision of the mass was undertaken. Intraoperatively, the mass appeared to be adjacent to the submandibular gland, but it had not invaded it. The mass was excised, and the submandibular gland was left in place. Pathology identified the tumor as a sialoblastoma. However, pathology also revealed that residual tumor was present at the surgical margin. The patient was returned to the operating room for excision of the left submandibular gland and the level I lymph nodes. Following revision surgery, the surgical margins were negative. The patient remained disease-free at the 1-year follow-up. Despite the need for revision surgery, this case provides support for the idea that surgery alone is sufficient for curative treatment.

Giant calculus of the submandibular salivary duct

April 30, 2006     Edwin K. Chan, MD; Nilesh D. Patel, MD

Epithelial-myoepithelial carcinoma

April 1, 2006     Gretchen S. Folk, DDS; Lester D.R. Thompson, MD, FASCP

Mucoepidermoid carcinoma

December 1, 2005     Lester D.R. Thompson, MD

Adenoid cystic carcinoma of the salivary glands: A 20-year review with long-term follow-up

September 30, 2005     Avi Khafif, MD; Yakir Anavi, DMD; Jacob Haviv, MD, MPH; Rafael Fienmesser, MD; Shlomo Calderon, DMD; Gideon Marshak, MD
The behavior of adenoid cystic carcinoma (ACC) of the salivary glands has been shown to be unpredictable in terms of local and distant spread and mortality. We retrospectively studied 35 operations in 34 patients who had had a pathologic diagnosis of ACC of the salivary glands and who had been treated over a 20-year period and followed for a minimum of 10 years. We analyzed the effect that different factors had on outcomes. The site of origin appeared to be an important factor in survival rates; survival among patients with tumors that had originated in the parotid gland was fairly good, while survival among those with tumors that originated in the minor salivary glands was significantly worse. TNM staging was another significant factor in survival. Other poor prognostic indicators were local spread, nodal positivity, distant metastasis, and local and regional recurrence. Radiation and chemotherapy did not appear to be beneficial for patients with advanced disease. We recommend radical surgery with complete resection for all patients with ACC of the salivary glands and a careful assessment of the neck in patients with minor salivary gland tumors.

Modified submandibular sialoadenectomy

November 1, 2004     Akhtar Hussain, FRCS; Daran P. Murray, AFRCSI
Submandibular sialoadenectomy is a common head and neck procedure. Indications include the presence of benign and malignant tumors and inflammatory disease with or without intraglandular sialolithiasis. The standard technique involves a variably sized incision. The facial artery and vein are usually ligated and transected during the procedure, and either suction or nonsuction wound drainage is generally instituted. We describe a modified sialoadenectomy technique that involves a minimal incision, preserves the facial artery and vein, and does not require wound drainage because the surgical site is closed in three layers. We performed this procedure on 19 patients and observed only 1 postoperative complication''mild paresis of the right marginal mandibular branch of the facial nerve following the excision of a Warthin's tumor. This patient recovered fully 3 months postoperatively.

A case of giant sialolith of the submandibular salivary gland

April 30, 2004     Altan Yildirim, MD

Sinonasal adenoid cystic carcinoma with widespread symptomatic bony metastasis

April 1, 2004     Wha-Joon Lee, MD, PhD; Silloo B. Kapadia, MD; Brendan C. Stack, Jr., MD
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