Parotid

Epidermoid carcinoma involving the parotid gland and orbital region: Case report of a rare entity

June 30, 2008     Sundus Aslan, MD, Haluk Yavuz, MD, Rana Altan-Yaycioglu, MD, Filiz Bolat, MD, and Nuri Ozgirgin, MD
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Abstract

Epidermoid carcinoma (also known as squamous cell carcinoma) of the parotid gland is more prevalent among the elderly, as are other head and neck tumors. In most cases it is observed either as a nodal metastasis of a primary tumor that drains into the parotid area or as a direct extension of a tumor that has originated in the upper dermis. Primary epidermoid carcinomas arising directly from the parotid gland are extremely rare. Similarly, secondary invasion of the orbital region by a neighboring tumor is more common than primary epidermoid carcinoma of the orbit, which is also rare. In this article, we discuss the diagnosis and treatment of a rare case of epidermoid carcinoma simultaneously invading the parotid gland and the orbit.

Multiple pilomatrixomas: Case report and literature review

March 31, 2008     Shashidhar Sadda Reddy, MD, MPH, Swarupa A. Gadre, MD, Patrick Adegboyega, MD, and Arun K. Gadre, MD
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Abstract

Pilomatrixoma is a rare, benign, circumscribed, calcifying epithelial neoplasm that is derived from hair matrix cells. Multiple pilomatrixomas are uncommon. We describe a case of multiple pilomatrixomas in a 23-year-old black woman who presented with lesions on her face and back. Based on the results of the clinical examination, she was provisionally diagnosed with either calcified sebaceous cysts or calcified lymph nodes. She underwent surgical excision of the masses. On histopathology, the lesions were identified as pilomatrixomas. We attribute our original failure to diagnose this condition to our lack of familiarity with it. We discuss the presentation, differential diagnosis, and other characteristics of pilomatrixomas.

Bilateral multinodular oncocytomas of the parotid arising in a background of bilateral oncocytic nodular hyperplasia

January 1, 2008     Jason Hyde, MD, Masayoshi Takashima, MD, Brennan Dodson, MD, and Sherif Said, MD, PhD
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Abstract

Oncocytic tumors of the major salivary glands are rare, accounting for less than 1% of all salivary gland tumors. When they do occur, these neoplasms typically present as solitary nodules that affect only one major salivary gland, usually the parotid. Multiple bilateral multinodular tumors are rare. We report the case of a 53-year-old woman with a case of synchronous multiple bilateral multinodular oncocytomas that arose in a background of bilateral oncocytic nodular hyperplasia in the parotid glands. The patient underwent superficial parotid resections, and at the 4-year follow-up, she exhibited no evidence of recurrence.

Deep-lobe parotid tumor presenting in the parapharyngeal space

December 1, 2007     Sofia Avitia, MD, Jason S. Hamilton, MD, and Ryan F. Osborne, MD, FACS

Osteoclast-like giant-cell tumor of the parotid with salivary duct carcinoma: Case report and cytologic, histologic, and immunohistochemical findings

September 30, 2007    
article

Maryam Kadivar, MD, APCP;
Yalda Nilipour, MD;
Alireza Sadeghipour, MD, APCP

Abstract


Primary giant-cell tumor of the salivary gland is a rare lesion with an incompletely characterized histogenesis. To the best of our knowledge, only 16 cases have been previously documented in the English-language literature. We report a new case, which occurred in a 75-year-old man who presented with a parotid mass and cervical lymphadenopathy. The patient underwent a left total parotidectomy and cervical lymph node dissection. As far as we know, ours is the only reported case of a primary giant-cell tumor of the salivary gland in which the patient presented with lymph node metastasis. Because so little is known about giant-cell tumor of the salivary gland, we use the occasion of this case report to describe the cytologic, histologic, and immunohistochemical characteristics that we observed.

Squamous cell carcinoma of the accessory parotid gland

September 30, 2007     Ryan F. Osborne, MD, FACS
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An 85-year-old man presented with a persistent right accessory parotid gland carcinoma after surgical resection and radiotherapy (figure 1). The patient had been initially diagnosed by fine-needle aspiration as having a moderately to well-differentiated keratinizing squamous cell carcinoma of the right accessory parotid gland.

Use of AlloDerm implant to improve cosmesis after parotidectomy

July 31, 2007     Suzanne M. Sachsman, MS; Dale H. Rice, MD
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Abstract
We evaluated the effectiveness and practicality of using AlloDerm, an acellular human dermal matrix graft, as an interpositional barrier in an attempt to improve the appearance of the surgical defect created by parotidectomy. We performed AlloDerm reconstruction in a series of 10 patients, and we found that normal contour was satisfactorily restored in all 10. We conclude that the use of an AlloDerm implant is a low-risk, practical option for repairing the surgical defect in postparotidectomy patients.

Parotid sialocele in a 10-year-old girl

January 1, 2007     Kevin D. Pereira, MD; Stacey L. Smith, MD; Ron B. Mitchell, MD

Toxoplasmosis lymphadenitis presenting as a parotid mass: A report of 2 cases

September 30, 2006     Ron G. Shashy, MD; Daniel Pinheiro, MD, PhD; Kerry D. Olsen, MD
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Abstract
Toxoplasmosis manifesting as a parotid mass is rare; our review of the literature found only 6 previously reported cases. We report 2 new cases. Both patients presented with a small, mobile left parotid mass, and both were successfully treated with a diagnostic superficial parotidectomy. In both cases, the patient had been regularly exposed to cats and had recently eaten undercooked meat. When evaluating a parotid mass, otolaryngologists should be aware of the infectious causes of parotid swelling and lymphadenopathy and consider the possibility of toxoplasmosis when the history and pathologic findings are not suggestive of more common diseases.

Polymorphous low-grade adenocarcinoma of the parotid gland

September 30, 2006     Ashli K. O'Rourke, MD; Christine G. Gourin, MD; Zane K. Wade, MD; Richard B. Hessler, MD
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Abstract
Polymorphous low-grade adenocarcinoma (PLGA) of the parotid gland is rare. We describe a new case in which the patient underwent parotidectomy only to experience an extensive recurrence 2 years later. The recurrence was treated with radical surgical excision and radiation therapy, and the patient remained disease-free at 5 years of follow-up. We also review the literature on primary parotid PLGA.

Sarcoidosis presenting as a solitary parotid mass

September 30, 2006     James T. McCormick, DO; E. Douglas Newton, MD; Stanley Geyer, MD; Philip F. Caushaj, MD
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Abstract
We describe an unusual case of sarcoidosis in which the patient presented with a discrete solitary parotid mass and no other manifestation of the disease. The diagnosis was based on the unexpected pathologic findings during examination of a superficial parotidectomy specimen. To the best of our knowledge, no such presentation has been previously reported in the English-language literature.

Primary carcinoid tumor of the parotid gland: A case report and review of the literature

July 31, 2006     Irvin M. Modlin, MD, PhD; Michael D. Shapiro, BS; Mark Kidd, PhD
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Abstract
Salivary gland tumors account for 3 to 6% of all head and neck neoplasms in adults. Some 70 to 85% of these lesions are found in the parotid. Carcinoid tumors, which represent a distinct and relatively uncommon subset of neuroendocrine tumors, are most commonly found in the gastrointestinal tract, although in rare cases they are known to occur in extragastrointestinal locations, including the larynx, middle ear, and pancreas. Malignancies of the parotid gland are uncommon (approximately 25% of parotid neoplasms), and to the best of our knowledge, a primary carcinoid tumor of the parotid has not been previously described in the literature. Reports of parotid carcinoid tumors during the past 30 years have described the presence of nonparotid primary carcinoid tumors (usually gastrointestinal) that had been diagnosed and treated several years prior to the presentation of the parotid lesion. Under such circumstances, the parotid lesion may be assumed to have been a metastatic rather than a primary carcinoid. This report documents what we believe is the first case of a primary carcinoid tumor of the parotid gland. We detail the clinical, surgical, radiologic, immunologic, and histochemical findings associated with its diagnosis, and we describe our management of this case. Although a primary carcinoid in this location is exquisitely rare, knowledge of such lesions is important because their management is substantially different from that of other parotid tumors. In particular, it is important to differentiate them from metastatic tumors from other sites.
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