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Parotid gland metastasis in Merkel cell carcinoma of the head and neck: A series of 14 cases

September 19, 2016  |  Kristine E. Day, MD; William R. Carroll, MD; Eben L. Rosenthal, MD


Merkel cell carcinoma (MCC) is a rare cutaneous cancer of neuroendocrine cell origin that occurs frequently on the head and neck. With a high incidence of local recurrence and regional and distant metastasis, it carries a poor prognosis. We performed a retrospective study to...

Accessory parotid gland tumors: A series of 4 cases

July 18, 2016  |  Takuya Kakuki, MD; Kenichi Takano, MD; Makoto Kurose, MD; Atsushi Kondo, MD; Tsuyoshi Okuni, MD; Noriko Ogasawara, MD; Tetsuo Himi, MD


Accessory parotid gland tumors are clinically rare, and their management remains unclear. In this article, we describe our experience with 4 patients-2 males and 2 females, aged 13 to 66 years-who were diagnosed with an accessory parotid gland tumor. All patients presented with...

OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report

April 30, 2016  |  Kiyoshi Makiyama, PhD, MD; Ryoji Hirai, PhD, MD; Fusako Iikuni, MD; Atsuo Ikeda, MD; Hirotaka Tomomatsu, MD


OK-432 is an immunomodulator that has been reported to be efficacious as an injection therapy for cervical lymphomas and ranulas. We performed OK-432 injection therapy to treat a cystadenocarcinoma of the parotid gland in a 72-year-old man. The 50 x 46-mm tumor was located in...

If cytology of Warthin tumor is accurate, can management be conservative?

April 30, 2016  |  Alexander C. Vlantis, FCS(SA)ORL; Siu Kwan Ng, FRCSEd; Chi Keung Mak, MRCS(Ed); Jackie M. Cheung, MBChB; Amy B. Chan, FHKC Path; C. Andrew van Hasselt, MMed(Otol)


We conducted a retrospective study to assess the accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of Warthin tumor and to evaluate the subsequent risk of conservative nonsurgical management. We reviewed the records of 75 patients (76 tumors) with a parotid...

Ultrasonography-guided minimally invasive removal of parotid calculi: A prudent approach

February 24, 2016  |  Uma Patnaik, MS, DNB; Sreejith Nair, MS; Atul Mishra, MD


The trend in modern salivary calculi surgery is toward minimally invasive procedures because these benign conditions do not warrant open salivary gland surgery. Since ultrasonography is readily available, highly specific, noninvasive, and cost-effective, we have used an...

Huge lipoma of the right parotid gland: Case report and review of 42 cases

January 22, 2016  |  Timuçin Baykul, DDS, PhD; M. Asım Aydın, DDS, DMD, PhD; Yavuz Fındık, DDS, PhD; Derya Yıldırım, DDS, PhD


Lipomas are rarely found in the parotid gland region. Because of their rarity at this site, they are not often considered in the differential diagnosis of parotid tumors. The parotid lipoma is a slowly growing, asymptomatic, freely movable, soft mass. Preoperative diagnosis is...

Vascular malformation with phleboliths involving the parotid gland: A case report with a review of the literature

October 31, 2015  |  Caleb Ho, MD; Benjamin L. Judson, MD; Manju L. Prasad, MD


Phleboliths within the parotid gland are exceedingly rare. We report a case of a venous malformation with multiple phleboliths that involved the left parotid gland and extended into the extraparotid tissue in a 43-year-old woman. We also review 13 similar cases that have been...

"Cannonball" delayed pulmonary metastases in parotid adenoid cystic carcinoma

October 31, 2015  |  David X. Liu, BS; Juan S. Gomez, MD; Enrique Palacios, MD, FACR; Jeremy Nguyen, MD

Optimal imaging studies for perineural invasion can be obtained with magnetic resonance imaging, which demonstrates abnormal enhancement of the cranial nerves involved.

Oncocytic mucoepidermoid carcinoma of the parotid gland: A case report and review of the literature

July 21, 2015  |  Deepali Jain, MD; Nabeen C. Nayak, MD


Oncocytic metaplasia rarely has been reported in mucoepidermoid carcinomas. Most salivary gland lesions with oncocytic change are benign; therefore, it is important to distinguish mucoepidermoid carcinoma from other entities that may show prominent oncocytic change. We report a...

Intraductal infusion of steroids in patients with Sjogren syndrome to treat painful salivary swelling: Report of 2 cases

June 5, 2015  |  Henry R. Diggelmann, MD; Henry T. Hoffman, MD, MS, FACS


Painful salivary swelling in patients with Sjögren syndrome presents the clinician with a difficult-to-manage condition, and treatment options are limited. We report 2 cases that demonstrate the utility of a clinic-based intraductal corticosteroid infusion for the treatment of...

Giant Stensen duct calculus

April 28, 2015  |  Wen-Sen Lai, MD; Jih-Chin Lee, MD; Yueng-Hsiang Chu, PhD; Ying-Nan Chang, MD

A sialolith in the anterior third of a Stensen duct usually can be extracted in a minimally invasive manner via trans-oral sialolithotomy to avoid the morbidity associated with a sialadenectomy.

A case of myoepithelioma mimicking a parotid cyst

January 19, 2015  |  Haldun Onuralp Kamburoglu, MD, FEBOPRAS; Aycan U. Kayikcioglu, MD; Cigdem Himmetoglu, MD


Myoepithelioma is an uncommon tumor of the myoepithelial cells that is considered to represent a distinct category of tumor by the World Health Organization. It accounts for less than 1% of all tumors that develop in the salivary glands. We describe the case of a 35-year-old...


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