Sinonasal teratocarcinosarcoma (SNTCS) is an extremely rare malignancy of the paranasal sinuses that possesses the histopathologic features of both teratomas and carcinosarcomas. We report the case of a 58-year-old white man who presented with a 1-year history of a gradually enlarging left-sided nasal mass. The patient had previously undergone endoscopic sinus surgery at another facility, and the final pathologic specimen was reported as an SNTCS with positive margins. He was then referred to our institution, where he underwent a craniofacial resection combined with endoscopic intranasal resection. Postoperatively, he received combined chemotherapy and irradiation. At 48 months of follow-up, he was alive without evidence of disease.
Sinonasal teratocarcinosarcoma (SNTCS) is an exceedingly rare malignant neoplasm of the paranasal sinuses. This tumor possesses the histopathologic features of both teratomas and carcinosarcomas. Its morphologic variations and similarities to other types of soft-tissue sarcomas pose a diagnostic challenge. Moreover, inadequate tumor sampling or a lack of awareness of this entity may lead to an erroneous diagnosis.