Recurrent pre-B-cell acute lymphoblastic leukemia in the middle ear: A form of granulocytic sarcoma

July 5, 2012 by David Manning, MD; Enrique Palacios, MD, FACR; Harold Neitzschman, MD, FACR
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Imaging Clinic

Leukemia of the middle ear easily can be misidentified as acute otitis media or Bell palsy. It occurs most often in children 2 to 5 years of age and in the elderly population.

     Extramedullary involvement of recurrent pre-B-cell acute lymphoblastic leukemia (ALL) is a rare entity seen only in a handful of cases reported during the past several decades. Since this form of recurrent leukemia of the middle ear is rare and the clinical manifestations can mimic acute otitis media and Bell palsy, it may not be readily recognized.1-4

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CitationEar Nose Throat J. 2012 July;91(7):272-274