Hyponatremia develops as a result of the inappropriate secretion of antidiuretic hormone. In rare cases, it develops as an iatrogenic complication. For example, acute iatrogenic post-tonsillectomy hyponatremia has been described in children following the infusion of hypo- or isotonic fluid. We report a case of rapidly developing post-tonsillectomy iatrogenic hyponatremia in a 5-year-old girl following an excessive infusion of hypotonic fluid. Her signs and symptoms began with nausea and vomiting and progressed to seizures and coma. We corrected the electrolyte disturbance by infusing a 3% sodium chloride solution until her neurologic manifestations disappeared, at which time her serum sodium concentration had risen back to 135 mEq/L. Otolaryngologists are not generally exposed to much information about hyponatremia, so we must be aware of its associated neurologic signs and symptoms.
Hyponatremia represents an abnormally low concentration of sodium in the serum (range of normal: 135 to 145 mEq/L). It is a serious condition that develops as a result of the inappropriate secretion of antidiuretic hormone.1 Iatrogenic hyponatremia is rare, and post-tonsillectomy hyponatremia is very rare.2 Iatrogenic hyponatremia may develop during the postoperative period following the infusion of hypo- or isotonic fluid.