Primary carcinosarcoma of the helix of the ear

November 1, 2005 by Vladimir Vincek, MD, PhD; Marjan Mirzabeigi, MD; Brian S. Jewett, MD; W. Jarrard Goodwin, MD
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Abstract
We report our histologic and immunohistochemical findings in a rare case of cutaneous carcinosarcoma involving the helix of the ear. The tumor exhibited cellular features of both basal cell and squamous cell carcinoma and a malignant mesenchymal component that was consistent with malignant fibrous histiocytoma. The epithelial component exhibited a positive immunohistochemical reaction to cytokeratin and a negative reaction to vimentin, whereas the mesenchymal component showed a positive immunohistochemical reaction to vimentin and a negative reaction to cytokeratin. To the best of our knowledge, this is only the third reported case of a carcinosarcoma of the ear and the second case in which it developed on the helix.

Full Text Article: VINCEK-11_05.pdf

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