Otomycosis in immunocompetent and immunocompromised patients: Comparative study and literature review

March 1, 2012
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A comparative clinical study was carried out that included 50 cases of otomycosis in immunocompetent patients and 50 cases of otomycosis in immunocompromised patients. Clinical presentation, predisposing factors, mycologic profile, and treatment outcomes were compared. Aspergillus spp were the most commonly isolated fungi in the immunocompetent group, and Candida albicans in the immunocompromised group. Bilateral involvement was more common in the immunocompromised group. All the patients were treated with topical clotrimazole ear drops. Four patients in the immunocompromised group did not respond to treatment with clotrimazole but were treated successfully with fluconazole ear drops. Three patients had a small tympanic membrane perforation due to otomycosis.


Otomycosis is a superficial, subacute, or chronic infection of the outer ear canal, usually unilateral, that is characterized by inflammation, pruritis, and scaling.1 It occurs because the protective lipid/acid balance of the ear is lost.2

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CitationEar Nose Throat J. 2012 March;91(3):114-121