Juvenile xanthogranuloma (JXG) is a benign, non-Langerhans cell histiocytic lesion that generally affects infants and children. These lesions characteristically appear as a solitary, yellow, cutaneous nodule of the head, neck, or trunk. Subcutaneous and extracutaneous forms can involve the gastrointestinal tract, kidney, lung, gonads, pericardium, central nervous system, temporal bone, larynx, and eye. We describe the clinical presentation, imaging, histochemical findings, and management of a solitary JXG of the tympanic membrane in a 17-month-old girl. The patient underwent surgical resection and was without disease several months following surgery and reconstruction of the defect. To the best of our knowledge, this is the first reported case of a JXG of the tympanic membrane.
Introduction Juvenile xanthogranuloma (JXG) is a benign, non-Langerhans cell histiocytic lesion that is most commonly found in or on the skin of the head, neck, or trunk. It was first described by Adamson in 1905 as congenital xanthoma multiplex.1In 1912, McDonagh renamed these lesions naevo-xantho-endotheliomata.2In 1954, Helwig and Hackney called the condition xanthogranulomabased on its histologic appearance.3
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