Juvenile xanthogranuloma of the nasal vestibule

October 8, 2012 by Wan-Ling Ho, MD; Kai-Chieh Chan, MD
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Rhinoscopic Clinic

The histopathologic hallmark of juvenile xanthogranuloma is the Touton giant cell, a multinucleated giant histiocyte whose rings of nuclei separate a central homogeneous core from a foamy periphery.

     A 5-year-old girl presented with a gradually growing tumor on her right nostril and associated nasal blockage of several months’ duration. Anterior rhinoscopy detected a smooth, well-demarcated, protruding, 0.5 × 0.5-cm tumor of the right nasal vestibule (figure 1). Multiple small, ectatic blood vessels were also identified on the surface.

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CitationEar Nose Throat J. 2012 October;91(10):418-419