March 31, 2007
by Sofia Avitia, MD; Jason S. Hamilton, MD; Ryan F. Osborne, MD
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Head and Neck Clinic
A 35-year-old woman presented with near-complete aphonia. She had undergone excision of a laryngeal polyp 1 year earlier. Pathologic examination revealed that the lesion was consistent with laryngeal amyloidosis. Postoperatively, she had experienced an initial improvement in her voice, but over the following 10 months, the dysphonia had returned. She also reported dyspnea while supine.
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