Radiation-induced osteosarcoma of the maxillary sinus

A 41-year-old man presented with an osteosarcoma involving the right maxillary sinus. The patient had a history of a right maxillary embryonal rhabdomyosarcoma that had been treated with chemoradiation 8 years earlier; this suggested a current diagnosis of radiation-induced osteosarcoma (RIO). Findings on the head and neck examination were normal except for cranial nerve V2 hypoesthesia.