Extramedullary plasmacytoma of the true vocal fold

August 10, 2012 by Nilantha De Zoysa, MRCS, DOHNS, BS; Belinda Sandler, MRCP, BSc; Kwame Amonoo-Kuofi, MRCS; Rajiv Swamy, FRCPath; Prasad Kothari, MDS, FDSRCS, FRCS(ORL–HNS); George Mochloulis, MD, CCST(ORL–HNS)
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Abstract

We report a rare case of extramedullary plasmacytoma (EMP) of the true vocal fold. Our patient, a 62-year-old woman, presented with dysphonia. On workup, fiberoptic laryngoscopy detected a lesion arising from the anterior half of her left true vocal fold. No evidence of other pathology was noted. The patient underwent radical radiotherapy, and the lesion resolved. Follow-up revealed no sign of recurrence. A type of myeloma, EMP is rare, especially in the larynx. To the best of our knowledge, our patient represents the sixth case of glottic EMP to be reported in the literature.

Introduction Extramedullary plasmacytoma (EMP) is a type of plasma cell tumor found outside the bone marrow. Isolated EMP in the head and neck is very rare, and its management, including staging and treatment, differs from that of other head and neck carcinomas. We report a case of EMP diagnosed in the larynx. We describe the management of this patient, we review the literature on this rarity, and we discuss the salient implications of the current evidence on management. Case report

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CitationEar Nose Throat J. 2012 August;91(8):E23-E25