Enchondroma of the skull base secondary to generalized enchondromatosis: A case report and review of the literature

November 22, 2011 by Derek J. Rogers, MD, Mark E. Boseley, MD, Mark J. Stephan, MD, Samuel Browd, MD, PhD, and David C. Semerad, MD
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Abstract

Generalized enchondromatosis, of which Ollier disease is the most common type, is a rare bone dysplasia characterized by multiple intraosseous tumors near growth-plate cartilage. These cartilaginous tumors have a propensity to transform into chondrosarcomas. Enchondromas of the skull base are exceedingly rare. We present the case of a patient with generalized enchondromatosis who developed a large enchondroma of the clivus, and we discuss the clinical presentation and potential treatments for this entity.

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