The effect of nasal steroid administration on intraocular pressure

June 30, 2007 by Christos Spiliotopoulos, MD; Nicholas S. Mastronikolis, MD, PhD; Ioannis K. Petropoulos, MD; Ephigenia K. Mela, MD, PhD; Panos D. Goumas, MD, PhD; Sotirios P. Gartaganis, MD, PhD
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Abstract
The effect of systemic steroid administration on intraocular pressure (IOP) is well established. However, less attention has been paid to the effect of steroids when administered in a nasal spray. We conducted a study to investigate a possible association between nasal steroids and elevated IOP in 54 patients who were being treated for allergic rhinitis. IOP was measured before the patients started therapy and thereafter every 5 days during that therapy. Follow-up ranged from 27 to 35 days (mean: 31). Statistical analysis revealed no significant elevation in IOP after nasal steroid administration. It seems that short-term administration of nasal steroids does not cause significant IOP elevation. Nevertheless, their long-term effects on this pressure should be investigated.

Full Text Article: SPILIOTOPOULOS-ENT-07_07.pdf

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