Proton pump inhibitors: Adverse effects

December 17, 2010 by Robert T. Sataloff, MD, DMA, FACS, Editor-in-Chief
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Editorial
Most otolaryngologists are now aware of the importance and high incidence of laryngopharyngeal reflux (LPR), especially in patients with voice complaints. Although many controversies remain regarding optimal diagnosis and treatment, long-term therapy with acid suppression is used commonly.

Most otolaryngologists are now aware of the importance and high incidence of laryngopharyngeal reflux (LPR), especially in patients with voice complaints. Although many controversies remain regarding optimal diagnosis and treatment, long-term therapy with acid suppression is used commonly. 1 Untreated reflux can have potentially serious consequences, possibly including esophageal and laryngeal carcinoma.

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