Chondromyxoid fibroma of the mastoid portion of the temporal bone: MRI and PET/CT findings and their correlation with histology

April 17, 2013
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We report a very rare case of a chondromyxoid fibroma of the mastoid portion of the temporal bone in a 38-year-old woman who presented with left-sided hearing loss. Magnetic resonance imaging identified an expansile mass in the left mastoid bone with a heterogeneous hyperintense signal on T2-weighted imaging and peripheral enhancement. Subsequent positron emission tomography/computed tomography identified erosive bony changes associated with hypermetabolism. The patient underwent an infratemporal fossa resection with a suboccipital craniectomy/cranioplasty. We briefly review the aspects of this case, including a discussion of the differential diagnosis and the correlation between histologic and imaging findings.


Chondromyxoid fibroma (CMF) is a slowly growing, benign bone tumor that is exceedingly rare within the temporal bone.1 Our review of the literature identified only 6 previously reported cases of CMF within the mastoid bone.1-6 We report a new case of CMF of the mastoid portion of the temporal bone, and we discuss the correlation between the histologic features and findings on magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT).

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