Castleman disease of the neck: An uncommon location

January 24, 2013 by Lorena Garza Garcia, MD; Enrique Palacios, MD, FACR; Alexander Quiroz-Casian, MD; Harold Neitzschman, MD, FACR
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Imaging Clinic

Patients with the hyaline vascular variant of Castleman disease tend to be asymptomatic, although some have complained of symptoms caused by compression of adjacent structures, and others have reported a palpable mass.

Castleman disease is an uncommon benign lymphoproliferative disorder characterized by hypervascular lymphoid hyperplasia.1,2 Approximately 75% of all cases are found in the mediastinum; 15% are found in the abdomen, retroperitoneum, or pelvis; and 10% occur in the head and neck.

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