Are topical quinolones safe for middle ear use in children?

September 30, 2006
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Safety is more important than efficacy, a concept originally expressed as, "First, do no harm." The purported safety issues that surround the use of topical fluoroquinolones are the systemic effects of its absorption and its effects on the ecology of the ear canal, middle ear, and nasopharynx.

Systemic effects

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