Angiomyomatous hamartoma in a submandibular lymph node: A case report

March 1, 2009
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Angiomyomatous hamartomas have been found almost exclusively in the inguinal and femoral lymph nodes; few reports of these lesions in the head and neck region have been published. We present a case of angiomyomatous hamartoma in the submandibular area, a site that has not been previously reported in the literature. The mass was initially diagnosed as an enlarged lymph node. When it did not regress following broad-spectrum antibiotic treatment, the patient, a 51-year-old woman, underwent an excisional biopsy. Histopathology identified the mass as an angiomyomatous hamartoma. At follow-up 3 years and 9 months postoperatively, the patient exhibited no evidence of recurrence on physical examination and computed tomography. Even though angiomyomatous hamartoma of the head and neck is rare, we suggest that otolaryngologists include it in the differential diagnosis of head and neck masses.


Lymph node architecture can be partially replaced in conditions such as lymph node infarction, vascular transformation of the sinuses, bacillary angiomatosis, and metastatic angiosarcoma.1-3 In 1992, Chan et al were the first to report an angiomyomatous hamartoma as an independent condition characterized by replacement of the nodal parenchyma with smooth-muscle cells and fibrous tissue arranged in a sclerotic stroma.4 Angiomyomatous hamartomas have been de

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