Amyloid tumor of the larynx associated with plasma cell infiltration: Differential diagnosis

December 1, 2004
| Reprints
Abstract
Localized amyloidosis of the larynx is uncommon, accounting for fewer than 1% of all benign laryngeal tumors. We report 2 cases of laryngeal amyloidosis in which dense plasma cell infiltrates were found in the vicinity of the amyloid deposits; in view of this finding, we suspected a hematologic disease''plasmacytoma in particular. However, molecular genetic analysis did not demonstrate any light-chain restriction, indicating that the plasma cells were of polyclonal origin and therefore consistent with chronic inflammation. We also discuss the available literature with respect to diagnostic and therapeutic procedures in patients with amyloidosis of the upper airway.

Full Text Article: dec-BENNING.pdf

ENT Journal provides full text articles to our registered members.
Please log in or sign up for a FREE membership to view the full content:

You may also like to: