Adult case of large sinonasal embryonal rhabdomyosarcoma with intracranial extension

April 17, 2013
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Imaging Clinic

Rhabdomyosarcomas often present with nonspecific symptoms such as headache, nasal congestion, proptosis, epistaxis, and cranial nerve palsies, reflecting extension to the base of the skull.

Rhabdomyosarcoma (RMS) is a malignant neoplasm derived from premature mesenchymal cells showing striated muscle differentiation. It is the most common soft-tissue malignancy in the pediatric population, occurring in the head and neck.1,2 In the adult population, RMS is extremely rare, carrying a poor prognosis, and the literature is limited on the management and outcome of this tumor.3

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