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Acute laryngitis superimposed on chronic laryngitis

| Reprints
February 25, 2013
by David N. Myerson, MD; Rima A. DeFatta, MD; Robert T. Sataloff, MD, DMA, FACS

Radiation-induced fibrosis can be found in tissues of the neck, pharynx, larynx, esophagus, ear, and temporomandibular joint. It is associated histologically with aggregates of macrophages, fibroblasts, vascular connective tissue changes, and deposition of extracellular matrix. This fibrosis can lead to strictures, stenosis, trismus, ulcerations, and scarring, which can present as dysphagia and dysphonia.

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