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Marginal-zone B-cell lymphoma of the bony palate presenting as sinusitis by Lisa Skultety Ayers, DO, Jacqueline Oxenberg, DO, Seth Zwillenberg, MD, and Mahmoud Ghaderi, DO | Tuesday, January 01, 2008 IntroductionThe information in this article was originally presented at the 90th annual clinical assembly of the American Osteopathic Colleges of Ophthalmology and Otolaryngology–Head and Neck Surgery; May 3-7, 2006; Orlando, Fla.Marginal-zone B-cell lymphoma of the bony palate is uncommon. Its presentation can be confusing and misleading because of vague, nonspecific symptoms and nondiagnostic pathologic specimens. As a result of these diagnostic challenges, the initiation of treatment is often delayed.We describe a new case of marginal-zone B-cell lymphoma of the bony palate in which these diagnostic challenges were encountered and overcome. By reporting this case, we hope to help physicians who might be faced with a similar circumstance to attain a diagnosis more quickly. To that end, we emphasize the need for obtaining sufficiently large tissue biopsies and focusing immediate attention on histologic evaluation, flow cytometry, and appropriate immunochemical studies. A rapid .../continued/
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